公开(公告)号：US20110192562A1

公开(公告)日：2011-08-11

申请号：US12674716

申请日：2010-01-15

申请人： Masashi Motoi ,  Kenshin Honda ,  Toyoharu Terada ,  Tatsuya Okada ,  Yoshitomo Satouchi ,  Kanji Takada

发明人： Masashi Motoi ,  Kenshin Honda ,  Toyoharu Terada ,  Tatsuya Okada ,  Yoshitomo Satouchi ,  Kanji Takada

IPC分类号： B21G3/18 ,  B21G1/00 ,  B21D31/00

CPC分类号： A61M37/0015 ,  A61M2037/003 ,  A61M2037/0046 ,  A61M2037/0053 ,  B29C59/02

摘要： Microneedle sheets are produced by injecting a needle raw material into a stamper formed with a concavity in a base material. However, because the stamper concavity is very small, there is the problem that air cannot escape due to air and surface tension of the material, thereby preventing a needle from being formed in part. The present invention provides a stamper for producing a microneedle sheet. The stamper comprises a sheet-like base material including a conical concavity formed from a first surface of the sheet-like base material toward a second surface thereof; and a through-hole formed from a bottom of the concavity toward the second surface. Air can escape via this through-hole, allowing a microneedle sheet which is filled with a needle raw material as far as the bottom of the concavity to be obtained.

摘要翻译： 通过将针状原料注入形成有基材的凹部的压模来制造微针片。 然而，由于压模凹度非常小，所以存在由于空气和材料的表面张力而不能逸出的空气，从而防止针部分形成的问题。 本发明提供一种用于制造微针片的压模。 压模包括片状基材，其包括由片状基材的第一表面朝向其第二表面形成的锥形凹部; 以及从凹部的底部朝向第二表面形成的通孔。 空气可以通过该通孔逸出，从而可以获得填充有针原料的微针片至达凹部的底部。