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公开(公告)号：US20150166563A1
公开(公告)日：2015-06-18
申请号：US14628205
申请日：2015-02-20
申请人： Sejal Patel , Justin Mao , Qian Liu , Rui Zheng , Tyler Harrison , Rohit Duvadie , Xin Chen , Frederic Zecri , Jay Larrow , Xuchun Zheng , Yizong Zhou , Jiong Ye , Yiping Ding , Yu Gai
发明人： Sejal Patel , Justin Mao , Qian Liu , Rui Zheng , Tyler Harrison , Rohit Duvadie , Xin Chen , Frederic Zecri , Jay Larrow , Xuchun Zheng , Yizong Zhou , Jiong Ye , Yiping Ding , Yu Gai
IPC分类号： C07D493/08 , A61K31/4439 , C07D417/14 , A61K31/422 , C07D417/12 , A61K31/433 , C07D413/12 , A61K31/4245 , C07D413/14 , A61K31/506
CPC分类号： C07D493/08 , A61K31/422 , A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/506 , A61K45/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K2300/00
摘要： The invention relates to compounds of formula (I): useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
摘要翻译： 本发明涉及式（I）化合物：可用于治疗由酰基辅酶 - 二酰基甘油酰基转移酶1（DGAT1）介导的病症，例如， 代谢紊乱。 本发明还提供了治疗这些病症的方法，以及用于治疗的化合物和组合物等。
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公开(公告)号：US08993619B2
公开(公告)日：2015-03-31
申请号：US13871586
申请日：2013-04-26
申请人： Sejal Patel , Justin Mao , Qian Liu , Rui Zheng , Tyler Harrison , Rohit Duvadie , Xin Chen , Frederic Zecri , Jay Larrow , Xuchun Zheng , Yizong Zhou , Jiong Ye , Yiping Ding , Yu Gai
发明人： Sejal Patel , Justin Mao , Qian Liu , Rui Zheng , Tyler Harrison , Rohit Duvadie , Xin Chen , Frederic Zecri , Jay Larrow , Xuchun Zheng , Yizong Zhou , Jiong Ye , Yiping Ding , Yu Gai
IPC分类号： A01N43/08 , A61K31/34 , A01N43/16 , A61K31/35 , A61K31/505 , A01N43/40 , A61K31/44 , A01N43/82 , A61K31/41 , A01N43/76 , A61K31/42 , C07D401/00 , C07D403/00 , C07D405/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00 , C07D285/12 , C07D285/14 , C07D513/00 , C07D271/10 , C07D271/12 , C07D498/00 , C07D263/00 , C07D263/34 , C07D493/08 , A61K31/422 , A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/506 , A61K45/06 , C07D413/12 , C07D417/12
CPC分类号： C07D493/08 , A61K31/422 , A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/506 , A61K45/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K2300/00
摘要： The invention relates to compounds of formula (I): useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
摘要翻译： 本发明涉及式（I）化合物：可用于治疗由酰基辅酶 - 二酰基甘油酰基转移酶1（DGAT1）介导的病症，例如， 代谢紊乱。 本发明还提供了治疗这些病症的方法，以及用于治疗的化合物和组合物等。
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公开(公告)号：US20130289058A1
公开(公告)日：2013-10-31
申请号：US13871586
申请日：2013-04-26
申请人： Sejal Patel , Justin Mao , Qian Lui , Rui Zheng , Tyler Harrison , Rohit Duvadie , Xin Chen , Frederic Zecri , Jay Larrow , Xuchun Zheng , Yizong Zhou , Jiong Ye , Yiping Ding , Yu Gai
发明人： Sejal Patel , Justin Mao , Qian Lui , Rui Zheng , Tyler Harrison , Rohit Duvadie , Xin Chen , Frederic Zecri , Jay Larrow , Xuchun Zheng , Yizong Zhou , Jiong Ye , Yiping Ding , Yu Gai
IPC分类号： C07D493/08 , A61K31/506 , A61K45/06 , A61K31/4245 , A61K31/422 , A61K31/4439 , A61K31/433
CPC分类号： C07D493/08 , A61K31/422 , A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/506 , A61K45/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , A61K2300/00
摘要： The invention relates to compounds of formula (I): useful for treating disorders mediated by acyl coA-diacylglycerol acyl transferase 1 (DGAT1), e.g. metabolic disorders. The invention also provides methods of treating such disorders, and compounds and compositions etc. for their treatment.
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