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公开(公告)号：US20090099195A1
公开(公告)日：2009-04-16
申请号：US12115169
申请日：2008-05-05
Applicant: Malken Bayrakdarian , Christophe Buon , Louis-David Cantin , Yun-Jin Hu , Xuehong Luo , Vijayaratnam Santhakumar , Miroslaw Tomaszewski
Inventor： Malken Bayrakdarian , Christophe Buon , Louis-David Cantin , Yun-Jin Hu , Xuehong Luo , Vijayaratnam Santhakumar , Miroslaw Tomaszewski
IPC: A61K31/519 , C07D487/04 , A61P13/10 , A61K31/496
CPC classification number: C07D487/04 , C07D519/00
Abstract: Compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4, and R5 and are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
Abstract translation: 式I化合物或其药学上可接受的盐：其中R1，R2，R3，R4和R5如本说明书中所定义，以及包括该化合物的盐和药物组合物的制备。 它们可用于治疗，特别是治疗疼痛。
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公开(公告)号：US20230406851A1
公开(公告)日：2023-12-21
申请号：US18160167
申请日：2023-01-26
Applicant: Christophe BUON , Louis-David CANTIN , Yun-Jin HU , Xuehong LUO , Miroslaw Jerzy TOMASZEWSKI
Inventor： Christophe BUON , Louis-David CANTIN , Yun-Jin HU , Xuehong LUO , Miroslaw Jerzy TOMASZEWSKI
IPC: C07D471/04 , A61P29/00
CPC classification number: C07D471/04 , A61P29/00
Abstract: This invention generally relates to substituted imidazopyridine compounds, particularly substituted 4-(imidazo[1,2-a]pyridin-2-yl)benzamide compounds and salts thereof. This invention also relates to pharmaceutical compositions and kits comprising such a compound, uses of such a compound (including, for example, treatment methods and medicament preparations), processes for making such a compound, and intermediates used in such processes.
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3.发明申请Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof 审中-公开吡咯并喹啉和哌啶喹啉衍生物，其制备方法，含有它们的组合物及其用途公开(公告)号：US20070161619A1
公开(公告)日：2007-07-12
申请号：US10597817
申请日：2005-02-02
Applicant: Yun-Jin Hu , Miroslaw Tomaszewski , Christopher Walpole
Inventor： Yun-Jin Hu , Miroslaw Tomaszewski , Christopher Walpole
IPC: A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/4745 , C07D471/02
CPC classification number: C07D471/04
Abstract: Compounds of general formula: wherein n, R1, R2, R3, R4 and Ar are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
Abstract translation: 通式的化合物：其中n，R 1，R 2，R 3，R 4和Ar分别为 如本说明书中所定义，以及其盐，对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
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