公开(公告)号：US20090047336A1

公开(公告)日：2009-02-19

申请号：US11840537

申请日：2007-08-17

申请人： Zhijun Yang ,  Wenhua Huang ,  Chi Sun Wong ,  Zhongzhen Zhao

发明人： Zhijun Yang ,  Wenhua Huang ,  Chi Sun Wong ,  Zhongzhen Zhao

IPC分类号： A61K31/137 ,  A61K47/06 ,  A61K9/127 ,  A61K9/14 ,  A61P11/00 ,  A61P11/06

CPC分类号： A61K9/127 ,  A61K9/0073 ,  A61K31/137

摘要： A new formulation of dehydrated lipid vesicles employs a vesicle preserver and permits the control of release and delivery of active pharmaceutical ingredients into the respiratory system for treatment in particular of asthma. The typical formulation provides controlled release of the active pharmaceutical ingredient from 0% to 100% from 0 to 72 hours after inhalation, changes the systemic administration to topical administration, allows prolonged therapeutic period for one administration, increased stability, with reduced dose, reduced systemic side effects, reduced toxicity.

摘要翻译： 脱水脂质囊泡的新配方使用囊泡保护剂，并且允许控制活性药物成分的释放和递送到呼吸系统中用于特别是哮喘的治疗。 典型的制剂在吸入后从0至72小时提供活性药物成分从0％至100％的受控释放，将全身给药改变为局部给药，允许延长治疗期，一次给药，增加稳定性，减少剂量，减少全身 副作用，毒性降低。