专利检索 ap:("03;KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE") AND inv:"Huda H. Al-Khalaf" 第 1 页

1.

发明授权
Method for generating human multipotent mammary stem cells from normal primary breast luminal cells 有权

公开(公告)号：US11834673B2

公开(公告)日：2023-12-05

申请号：US17398328

申请日：2021-08-10

申请人： 03;KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE

发明人： Abdelilah Aboussekhra , Huda H. Al-Khalaf , Hazem Ghebeh

IPC分类号： C12N5/071 , A61K35/55

CPC分类号： C12N5/0631 , A61K35/55 , C12N2501/2308 , C12N2513/00

摘要： The invention relates to methods for generating multipotent mammary stern cells from isolated and cultured human breast luminal cells. The method comprises the steps: 1. isolating and growing normal differentiated cells in vitro; 2. treating the differentiated cells with either a conditioned medium from active fibroblasts or cytokine. The invention also relates to multipotent mammary stem cells, cultures of the multipotent stem cells, differentiated cells, tissues, organs derived from the culture multipotent stem cells isolated by the methods disclosed and therapeutic and other uses for those cells thereof.