公开(公告)号：US20240177348A1

公开(公告)日：2024-05-30

申请号：US18513046

申请日：2023-11-17

Applicant: 10x Genomics, Inc.

Inventor： Anton SHUTOV ,  Denis PRISTINSKI ,  Dmitri SIMONIAN

IPC: G06T7/80 ,  G06T7/73

CPC classification number: G06T7/85 ,  G06T7/74 ,  G06T2200/04 ,  G06T2207/10012 ,  G06T2207/20056

Abstract: A machine vision system for calibrating and/or positioning of various motion control modules of an opto-fluidic instrument/tool/instrument having integrated optics and fluidics modules configured for imaging of biological specimens is disclosed. The machine vision system includes determining 3D positions of an object within a reference coordinate system based on a plurality of stereo-images comprising the object; generating a transformation matrix based on the determined 3D positions of the object with respect to a reference position; and calibrating one or more motion control systems based on the determined transformation matrix. The methods also include determining a 3D position of an object within a reference coordinate system based on a stereo-image of the object; generating a 3D offset value between the determined 3D position and a reference location of the object; updating the 3D position using the 3D offset value; and positioning the object based on the corrected 3D position.

公开(公告)号：US20240171723A1

公开(公告)日：2024-05-23

申请号：US18513143

申请日：2023-11-17

Applicant: 10x Genomics, Inc.

Inventor： Anton SHUTOV ,  Denis PRISTINSKI

IPC: H04N13/246 ,  H04N13/207 ,  H04N13/254

CPC classification number: H04N13/246 ,  H04N13/207 ,  H04N13/254

Abstract: An optical assembly of a machine vision system for calibrating and/or positioning of various motion control modules of an analytical system/tool/instrument having integrated optics and fluidics modules configured for imaging of biological specimens is disclosed. The optical assembly includes one or more light sources configured to generate a first light beam and a second light beam that intersects the first light beam at an intersection region to illuminate an object within the intersection region; a sensor array configured to receive the first light beam and the second light beam to thereby form a stereo-image based on received light from the first light beam and the second light beam; a first imaging mirror configured to reflect the first beam after the intersection region and towards the sensor array; and a second imaging mirror configured to reflect the second beam after the intersection region and towards the sensor array.