公开(公告)号：US20150126747A1

公开(公告)日：2015-05-07

申请号：US14365607

申请日：2012-05-25

Applicant: ABBVIE INC.

Inventor： Allan Krueger ,  Warren M. Kati ,  Clarence J. Maring ,  Rolf Wagner ,  Charles W. Hutchins

IPC: C07D487/04

CPC classification number: C07D487/04 ,  A61K31/407 ,  A61K31/4162

Abstract: The present invention relates to anti-HCV compounds, compositions comprising the same and methods of using the same to treat HCV infection.

公开(公告)号：US09464082B2

公开(公告)日：2016-10-11

申请号：US14604129

申请日：2015-01-23

Applicant: AbbVie Inc. ,  Reata Pharmaceuticals, Inc.

Inventor： Pamela Donner ,  Rolf Wagner ,  Jason Shanley ,  Howard Heyman ,  Allan Krueger ,  Hui-Ju Chen ,  Michael Rozema ,  David Grampovnik ,  Melean Visnick ,  Eric Anderson ,  Xin Jiang ,  Christopher F. Bender ,  Gary Louis Bolton ,  Bradley William Caprathe ,  Chitase Lee ,  William Howard Roark

IPC: C07D231/54 ,  C07D239/70 ,  C07D239/72 ,  C07D401/04 ,  C07D403/04 ,  C07D417/04 ,  C07D471/04 ,  C07D413/04

CPC classification number: C07D471/04 ,  C07D231/54 ,  C07D239/70 ,  C07D239/72 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D417/04

Abstract: The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein R1, R2, R3, R4, R5, R6, m, n, X and Y are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use for the treatment and prevention of diseases such as those associated with oxidative stress and inflammation.

公开(公告)号：US20150225397A1

公开(公告)日：2015-08-13

申请号：US14604129

申请日：2015-01-23

Applicant: AbbVie Inc. ,  Reata Pharmaceuticals, Inc.

Inventor： Pamela Donner ,  Rolf Wagner ,  Jason Shanley ,  Howard Heyman ,  Allan Krueger ,  Hui-Ju Chen ,  Michael Rozema ,  David Grampovnik ,  Melean Visnick ,  Eric Anderson ,  Xin Jiang ,  Christopher F. Bender ,  Gary Louis Bolton ,  Bradley William Caprathe ,  Chitase Lee ,  William Howard Roark

IPC: C07D471/04 ,  C07D231/54 ,  C07D413/04 ,  C07D403/04 ,  C07D417/04 ,  C07D239/70 ,  C07D401/04

CPC classification number: C07D471/04 ,  C07D231/54 ,  C07D239/70 ,  C07D239/72 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D417/04

Abstract: The present application relates to: (a) compounds of Formula (I): and salts thereof, wherein R1, R2, R3, R4, R5, R6, m, n, X and Y are as defined in the specification; (b) compositions comprising such compounds and salts; and (c) methods of use of such compounds, salts, and compositions, particularly use for the treatment and prevention of diseases such as those associated with oxidative stress and inflammation.

Abstract translation: 本申请涉及：（a）式（I）化合物及其盐，其中R 1，R 2，R 3，R 4，R 5，R 6，m，n，X和Y如说明书中所定义; （b）包含这些化合物和盐的组合物; 和（c）使用这些化合物，盐和组合物的方法，特别用于治疗和预防与氧化应激和炎症有关的疾病。

公开(公告)号：US20150105548A1

公开(公告)日：2015-04-16

申请号：US14365611

申请日：2012-05-25

Applicant: ABBVIE INC

Inventor： Allan Krueger ,  Warren M. Kati ,  Clarence J. Maring ,  Rolf Wagner ,  Charles W. Hutchins

IPC: C07D513/04 ,  C07D498/04 ,  C07D471/04 ,  C07D487/04

CPC classification number: C07D513/04 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

Abstract: The present invention relates to anti-HCV compounds, compositions comprising the same and methods of using the same to treat HCV infection.