公开(公告)号：US20140213595A1

公开(公告)日：2014-07-31

申请号：US14017901

申请日：2013-09-04

Applicant: ABBVIE INC.

Inventor： David A. DEGOEY ,  Pamela L. DONNER ,  Warren M. KATI ,  Charles W. HUTCHINS ,  Allan C. KRUEGER ,  John T. RANDOLPH ,  Christopher E. MOTTER ,  Preethi KRISHNAN ,  Neeta C. MISTRY ,  Tami J. PILOT-MATIAS ,  Sachin V. PATEL ,  Xiaoyan LI ,  Todd N. SOLTWEDEL ,  Lissa T. NELSON

IPC: C07D471/04 ,  C07D239/48

CPC classification number: C07D471/04 ,  C07D239/48

Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Abstract translation: 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。

公开(公告)号：US20190262465A1

公开(公告)日：2019-08-29

申请号：US16408602

申请日：2019-05-10

Applicant: AbbVie Inc.

Inventor： Michael J. MCPHERSON ,  Adrian D. HOBSON ,  Martin E. HAYES ,  Christopher C. MARVIN ,  Diana SCHMIDT ,  Wendy WAEGELL ,  Christian GOESS ,  Jason Z. OH ,  Axel HERNANDEZ, Jr. ,  John T. RANDOLPH

IPC: A61K47/68 ,  A61P37/06 ,  C07J71/00 ,  C07K16/24

Abstract: Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same, e.g., to treat autoimmune or inflammatory diseases.

公开(公告)号：US20180126000A1

公开(公告)日：2018-05-10

申请号：US15611037

申请日：2017-06-01

Applicant: AbbVie Inc.

Inventor： Michael J. MCPHERSON ,  Adrian D. HOBSON ,  Martin E. HAYES ,  Christopher C. MARVIN ,  Diana SCHMIDT ,  Wendy WAEGELL ,  Christian GOESS ,  Jason Z. OH ,  Axel HERNANDEZ, JR. ,  John T. RANDOLPH

IPC: A61K47/68 ,  C07K16/24

Abstract: Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same, e.g., to treat autoimmune or inflammatory diseases.