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1.发明申请OXINDOLE DERIVATIVES CARRYING AN AMINE-SUBSTITUTED PIPERIDYL-AZETIDINYL SUBSTITUENT AND USE THEREOF FOR TREATING VASOPRESSINE-RELATED DISEASES 有权实施胺取代的哌嗪 - 亚胺基替代物的氧化衍生物及其用于治疗与维生素A相关的疾病的用途公开(公告)号：US20170001982A1
公开(公告)日：2017-01-05
申请号：US15106662
申请日：2014-12-19
Applicant: ABBVIE DEUTSCHLAND GMBH & CO. KG , ABBVIE INC.
Inventor： Hervé GENESTE , Wilfried HORNBERGER , Charles W. HUTCHINS , Katja JANTOS , Andreas KLING , Loic LAPLANCHE , Marcel VAN GAALEN
IPC: C07D401/14
CPC classification number: C07D401/14
Abstract: The present invention relates to novel substituted oxindole derivatives of formula (I) wherein the variables are as defined in the claims and description; to pharmaceutical compositions comprising them, and to their use for the treatment of vasopressin-related disorders.
Abstract translation: 本发明涉及式（I）的新型取代的羟基吲哚衍生物，其中变量如权利要求和说明书所定义; 包含它们的药物组合物及其用于治疗加压素相关病症的用途。
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Patent Agency Ranking
2.发明申请ISOINDOLINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY 有权ISOINDOLINE衍生物，含有它们的药物组合物及其在治疗中的使用公开(公告)号：US20130210880A1
公开(公告)日：2013-08-15
申请号：US13764454
申请日：2013-02-11
Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
Inventor： Wilhelm Amberg , Udo LANGE , Michael OCHSE , Frauke POHLKI , Charles W. HUTCHINS , Irini ZANZE , Hongyu H. ZHAO , Huan-Qiu LI , Ying X. WANG
IPC: C07D209/46 , C07D405/14 , C07D403/12
CPC classification number: C07D209/46 , C07D209/44 , C07D403/12 , C07D405/14
Abstract: The present invention relates to isoindoline derivatives of the formula (I) or a physiologically tolerated salt thereof.The present invention also relates to pharmaceutical compositions comprising such isoindoline derivatives, and the use of such isoindoline derivatives for therapeutic purposes.
Abstract translation: 本发明涉及式（I）的异二氢吲哚衍生物或其生理耐受盐。 本发明还涉及包含这种异二氢吲哚衍生物的药物组合物，以及用于治疗目的的这种异吲哚啉衍生物的用途。
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3.发明申请OXINDOLE DERIVATIVES CARRYING A PIPERIDYL-SUBSTITUTED AZETIDINYL SUBSTITUENT AND USE THEREOF FOR TREATING VASOPRESSINE-RELATED DISEASES 有权携带哌啶取代的亚胺基取代基的氧化衍生物及其用于治疗类风湿关节疾病的用途公开(公告)号：US20170008875A1
公开(公告)日：2017-01-12
申请号：US15106670
申请日：2014-12-19
Applicant: ABBVIRE DEUTSCHLAND GMBH & CO. KG , ABBVIE INC.
Inventor： Hervé GENESTE , Wilfried HORNBERGER , Charles W. HUTCHINS , Katja JANTOS , Andreas KLING , Loic LAPLANCHE , Marcel VAN GAALEN
IPC: C07D401/14 , C07D405/14 , C07D491/107 , C07B59/00
CPC classification number: C07D401/14 , C07B59/002 , C07B2200/05 , C07D401/04 , C07D405/14 , C07D491/107
Abstract: The present invention relates to novel substituted oxindole derivatives of formula (I) wherein the variables are as defined in the claims and description; to pharmaceutical compositions comprising them, and to their use for treatment of vasopressin-related disorders.
Abstract translation: 本发明涉及式（I）的新型取代的羟基吲哚衍生物，其中变量如权利要求和说明书所定义; 包含它们的药物组合物及其用于治疗加压素相关病症的用途。
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公开(公告)号：US20140213601A1
公开(公告)日：2014-07-31
申请号：US14021435
申请日：2013-09-09
Applicant: ABBVIE INC.
Inventor： David A. DEGOEY , Pamela L. DONNER , Warren M. KATI , Charles W. HUTCHINS , Mark A. MATULENKO , Tammie K. JINKERSON , Ryan G. KEDDY
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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公开(公告)号：US20140213595A1
公开(公告)日：2014-07-31
申请号：US14017901
申请日：2013-09-04
Applicant: ABBVIE INC.
Inventor： David A. DEGOEY , Pamela L. DONNER , Warren M. KATI , Charles W. HUTCHINS , Allan C. KRUEGER , John T. RANDOLPH , Christopher E. MOTTER , Preethi KRISHNAN , Neeta C. MISTRY , Tami J. PILOT-MATIAS , Sachin V. PATEL , Xiaoyan LI , Todd N. SOLTWEDEL , Lissa T. NELSON
IPC: C07D471/04 , C07D239/48
CPC classification number: C07D471/04 , C07D239/48
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
Abstract translation: 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。
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公开(公告)号：US20140155382A1
公开(公告)日：2014-06-05
申请号：US14087480
申请日：2013-11-22
Applicant: ABBVIE INC.
Inventor： David A. DEGOEY , Allan C. KRUEGER , Charles W. HUTCHINS , Warren M. KATI , William A. CARROLL
IPC: A61K31/55 , A61K31/422 , A61K31/4184 , A61K31/4178 , A61K45/06 , C07D487/04 , C07D417/14 , C07D413/12 , C07D403/14 , C07D207/16 , A61K31/506 , A61K31/4025
CPC classification number: A61K31/55 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/422 , A61K31/506 , A61K38/00 , A61K45/06 , C07D205/04 , C07D207/16 , C07D207/22 , C07D209/52 , C07D211/60 , C07D263/06 , C07D277/06 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D487/04 , C07K5/06034 , C07K5/06043 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06139
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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