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公开(公告)号：US20210346369A1
公开(公告)日：2021-11-11
申请号：US17108719
申请日：2020-12-01
Applicant: AbbVie Inc.
Inventor： Le WANG , George DOHERTY , Xilu WANG , Zhi-Fu TAO , Milan BRUNCKO , Aaron R. KUNZER , Michael D. WENDT , Xiaohong SONG , Robin FREY , Todd M. HANSEN , Gerard M. SULLIVAN , Andrew JUDD , Andrew SOUERS
IPC: A61K31/4725 , C07D471/04 , A61K31/5377 , A61K45/06 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
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2.发明申请公开(公告)号：US20200345717A1
公开(公告)日：2020-11-05
申请号：US16719794
申请日：2019-12-18
Applicant: AbbVie Inc.
Inventor： Le WANG , George DOHERTY , Xilu WANG , Zhi-Fu TAO , Milan BRUNCKO , Aaron R. KUNZER , Michael D. WENDT , Xiaohong SONG , Robin FREY , Todd M. HANSEN , Gerard M. SULLIVAN , Andrew JUDD , Andrew SOUERS
IPC: A61K31/4725 , C07D471/04 , A61K31/5377 , A61K45/06 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
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3.发明公开公开(公告)号：US20240285611A1
公开(公告)日：2024-08-29
申请号：US18450394
申请日：2023-08-15
Applicant: ABBVIE INC.
Inventor： Le WANG , George DOHERTY , Xilu WANG , Zhi-Fu TAO , Milan BRUNCKO , Aaron R. KUNZER , Michael D. WENDT , Xiaohong SONG , Robin FREY , Todd M. HANSEN , Gerard M. SULLIVAN , Andrew JUDD , Andrew SOUERS
IPC: A61K31/4725 , A61K31/4985 , A61K31/5025 , A61K31/5377 , A61K31/541 , C07D401/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D493/08 , C07D513/04
CPC classification number: A61K31/4725 , A61K31/4985 , A61K31/5025 , A61K31/5377 , A61K31/541 , C07D401/04 , C07D417/14 , C07D471/04 , C07D487/04 , C07D493/08 , C07D513/04
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
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4.发明申请公开(公告)号：US20180221363A1
公开(公告)日：2018-08-09
申请号：US15845835
申请日：2017-12-18
Applicant: AbbVie Inc.
Inventor： Le WANG , George DOHERTY , Xilu WANG , Zhi-Fu TAO , Milan BRUNCKO , Aaron R. KUNZER , Michael D. WENDT , Xiaohong SONG , Robin FREY , Todd M. HANSEN , Gerard M. SULLIVAN , Andrew JUDD , Andrew SOUERS
IPC: A61K31/4725 , C07D417/14 , C07D471/04 , A61K31/5377 , A61K45/06
CPC classification number: A61K31/4725 , A61K31/5377 , A61K45/06 , C07D417/14 , C07D471/04
Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
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