公开(公告)号：US10093635B2

公开(公告)日：2018-10-09

申请号：US15814322

申请日：2017-11-15

Applicant: ABIDE THERAPEUTICS, INC.

Inventor： Cheryl A. Grice ,  Daniel J. Buzard ,  Michael B. Shaghafi

IPC: C07D295/195

Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.

公开(公告)号：US10030020B2

公开(公告)日：2018-07-24

申请号：US15593239

申请日：2017-05-11

Applicant: Abide Therapeutics, Inc.

Inventor： Justin S. Cisar ,  Cheryl A. Grice ,  Todd K. Jones ,  Olivia D. Weber ,  Daniel J. Buzard ,  Michael B. Shaghafi

IPC: C07D471/10 ,  C07D519/00

Abstract: Provided herein are spirocycle compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.