公开(公告)号：US20220120757A1

公开(公告)日：2022-04-21

申请号：US17502399

申请日：2021-10-15

Applicant: ACADEMIA SINICA

Inventor： Huan-Cheng CHANG ,  Yuen-Yung HUI ,  Hsin-Hung LIN ,  Oliver Y. CHEN

IPC: G01N33/58 ,  G01N33/543 ,  G01N21/64

Abstract: The present disclosure discloses a detection method and a detection system for detecting an object of interest in a biological sample. The detection method comprises the following steps: providing a detection kit comprising a detection carrier and a reporter, wherein the detection carrier comprises a coating protein having a recognition site for binding the object of interest, the reporter including a spin luminescent material; mixing the reporter and the biological sample and loading the mixture onto the detection carrier; placing the detection carrier with the mixture of the reporter molecule and the biological sample in a time-varied physical field; irradiating a detection carrier placed in the time-varied physical field with an excitation light to excite the spin luminescent material to generate a fluorescence signal modulated by the time-varied physical field; and receiving and analyzing the fluorescence signal.