公开(公告)号：US20240316014A1

公开(公告)日：2024-09-26

申请号：US18126273

申请日：2023-03-24

Applicant: ACADEMIA SINICA ,  GWO XI STEM CELL APPLIED TECHNOLOGY CO., LTD.

Inventor： Joyce Jean LU ,  Hsiao-Chun Huang ,  Pei-Lun La ,  Chi-Hou Ng ,  Ming-Hsi Chuang

IPC: A61K31/44 ,  A61K9/00 ,  A61K31/352 ,  A61K31/404 ,  A61P25/00

CPC classification number: A61K31/44 ,  A61K9/0019 ,  A61K9/0085 ,  A61K31/352 ,  A61K31/404 ,  A61P25/00

Abstract: The present invention generally relates to a method for treating a demyelinating condition, in particular, by administering a combination comprising therapeutically effective amounts of a Rho-associated protein kinase (ROCK) inhibitor, a cyclin-dependent kinase (CDK) inhibitor, and a cyclic adenosine monophosphate (cAMP) activator to a subject in need thereof.