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1.发明公开公开(公告)号：US20240101602A1
公开(公告)日：2024-03-28
申请号：US18038592
申请日：2021-11-24
Applicant: ACADEMIA SINICA , NATIONAL TAIWAN UNIVERSITY
Inventor： Rita P.Y. Chen , Chiu-Ping CHENG , Chien-Chih YANG , Kung-Ta LEE , Ying-Lien CHEN , Li-Hang Hsu , Hsin-Liang CHEN , Sung CHEN
Abstract: Provided is a peptide and method in preventing or treating infections caused by a wide spectrum of pathogens, including bacteria and fungus in hosts such as plants and animals. Methods of preventing or treating plant diseases and infection in animals are also provided.
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公开(公告)号：US11160790B2
公开(公告)日：2021-11-02
申请号：US16714867
申请日：2019-12-16
Applicant: NATIONAL TAIWAN UNIVERSITY
Inventor： Ying-Lien Chen , Hao-Tai Ko , Li-Hang Hsu , Sheng-Yung Yang
IPC: A61K31/4152 , A61P31/10 , A61K31/436
Abstract: Provided is a method of inhibiting the growth of a fungus using eltrombopag, wherein the fungus is selected from the group consisting of Cryptococcus, Candida glabrata, and Trichophyton rubrum. Also provided are a combination agent that includes eltrombopag and a macrolide calcineurin inhibitor and a method of using the combination agent for inhibiting the growth of Cryptococcus. Also provided is a method of inhibiting virulence factor formation in Cryptococcus using eltrombopag.
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公开(公告)号：US20210121443A1
公开(公告)日：2021-04-29
申请号：US16714867
申请日：2019-12-16
Applicant: NATIONAL TAIWAN UNIVERSITY
Inventor： Ying-Lien Chen , Hao-Tai Ko , Li-Hang Hsu , Sheng-Yung Yang
IPC: A61K31/4152 , A61K31/436 , A61P31/10
Abstract: Provided is a method of inhibiting the growth of a fungus using eltrombopag, wherein the fungus is selected from the group consisting of Cryptococcus, Candida glabrata, and Trichophyton rubrum. Also provided are a combination agent that includes eltrombopag and a macrolide calcineurin inhibitor and a method of using the combination agent for inhibiting the growth of Cryptococcus. Also provided is a method of inhibiting virulence factor formation in Cryptococcus using eltrombopag.
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