公开(公告)号：US11274092B2

公开(公告)日：2022-03-15

申请号：US16078128

申请日：2017-02-23

申请人： ACESION PHARMA ApS

发明人： Ulrik Svane Sørensen ,  Antonio Mete

IPC分类号： C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  C07D403/12 ,  C07D417/12 ,  C07D491/107 ,  C07D235/30 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10

摘要： The present invention relates to a compound of the general formula (I). The compounds of formula I are useful for treatment of a cardiac disease, disorder or condition in a mammal.

公开(公告)号：US11098018B2

公开(公告)日：2021-08-24

申请号：US16638590

申请日：2018-08-13

申请人： ACESION PHARMA ApS

发明人： Ulrik Svane Sørensen ,  Antonio Mete

IPC分类号： C07D235/30

摘要： A compound of the general formula (I). The compounds of formula I are useful for treatment of a cardiac disease, disorder or condition in a mammal.

公开(公告)号：US11168074B2

公开(公告)日：2021-11-09

申请号：US16639214

申请日：2018-08-22

申请人： ACESION PHARMA ApS

发明人： Ulrik Svane Sørensen ,  Antonio Mete

IPC分类号： C07D403/12 ,  C07D235/30 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12

摘要： A compound of the general formula (I). The compounds of formula I are useful for treatment of a cardiac disease, disorder or condition in a mammal.

公开(公告)号：US12030856B2

公开(公告)日：2024-07-09

申请号：US18238732

申请日：2023-08-28

申请人： ACESION PHARMA APS

发明人： Antonio Mete ,  Ulrik Sørensen

IPC分类号： C07D233/88

CPC分类号： C07D233/88

摘要： A compound of the general formula (I), and the pharmaceutical composition including a compound of formula (I) and optionally a pharmaceutically acceptable additive. Also, the treatment of a cardiac disease, disorder or condition in a mammal, which includes the administration to the mammal a therapeutically effective amount of at least one compound of formula (I), or the pharmaceutically acceptable salt thereof.

公开(公告)号：US11945811B2

公开(公告)日：2024-04-02

申请号：US18239348

申请日：2023-08-29

申请人： ACESION PHARMA APS

发明人： Antonio Mete ,  Ulrik Sørensen

IPC分类号： C07D413/12 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D413/06 ,  C07D417/06

CPC分类号： C07D413/06 ,  C07D403/06 ,  C07D403/12 ,  C07D413/12 ,  C07D417/06

摘要： A compound of the general formula (I), and the pharmaceutical composition including a compound of formula (I) and optionally a pharmaceutically acceptable additive. Also, the treatment of a cardiac disease, disorder or condition in a mammal, which includes the administration to the mammal a therapeutically effective amount of at least one compound of formula (I), or the pharmaceutically acceptable salt thereof.