公开(公告)号：US20240174620A1

公开(公告)日：2024-05-30

申请号：US18280120

申请日：2022-03-04

Applicant: ADAMA AGAN LTD.

Inventor： Michael GRABARNICK ,  Sergio NAHMOUD ,  Daniel MELIKER ,  Lior ZISERMAN ,  Ashok Kumar JHA ,  Revanappa Vasantrao GALGE

IPC: C07D239/54 ,  A01N43/54 ,  A01P13/00

CPC classification number: C07D239/54 ,  A01N43/54 ,  A01P13/00

Abstract: The present invention relates to novel solid forms of saflufenacil-sodium or saflufenacil-potassium. The present invention further relates to a process of making said novel solid forms of saflufenacil-sodium or saflufenacil-potassium. Still further, the present invention relates to the use of the novel solid forms of saflufenacil-sodium or saflufenacil-potassium.

公开(公告)号：US20240217915A1

公开(公告)日：2024-07-04

申请号：US18552326

申请日：2022-03-22

Applicant: ADAMA AGAN LTD.

Inventor： Michael GRABARNICK ,  Ashok Kumar JHA ,  Revanappa Vasantrao GALGE

IPC: C07C201/16 ,  A01N43/54 ,  A01P13/00 ,  C07C201/08 ,  C07D239/54

CPC classification number: C07C201/16 ,  A01N43/54 ,  A01P13/00 ,  C07C201/08 ,  C07D239/54

Abstract: The present invention relates to a novel nitration process of 2-chloro-4-fluorobenzoic acid to 2-chloro-4-fluoro-5-ni-trobenzoic acid, 2-chloro-4-f luoro-3-nitrobenzoic acid and 3,5-dinitro-2-chloro-4-fluorobenzoic acid; purifying the crude reaction product; and recovering 2-chloro-4-fluoro-5-nitrobenzoic acid in an essentially pure form, which can be used in the synthesis of the herbicide saflufenacil.

公开(公告)号：US20250115560A1

公开(公告)日：2025-04-10

申请号：US18294602

申请日：2022-08-09

Applicant: ADAMA AGAN LTD.

Inventor： Michael GRABARNICK ,  Ashok Kumar JHA ,  Revanappa Vasantrao GALGE

IPC: C07D239/557

Abstract: The invention relates to a novel and efficient saflufenacil synthesis and the preparation of novel key intermediates in the process of Saflufenacil synthesis. The process includes preparing compounds of the Formula I wherein R1i is a hydrogen, C1-12 straight or branched alkyl, which may be substituted with 1 or more substituents, a C3-10 cycloalkyl, which may be substituted with 1 or more substituents, a C6-10 aromatic ring which may be substituted with 1 or more substituents, a C5-10 heteroaromatic ring, which may be substituted with 1 or more substituents; R2 is a hydrogen or methyl.