公开(公告)号：US20210147362A1

公开(公告)日：2021-05-20

申请号：US17254952

申请日：2019-06-24

Applicant: ADAMA AGAN LTD.

Inventor： Avihai YACOVAN ,  Omer TZOR

IPC: C07D215/48

Abstract: It is an object of the present invention to provide a novel and advantageous process for commercially preparing quinmerac.

公开(公告)号：US20170081299A1

公开(公告)日：2017-03-23

申请号：US15364688

申请日：2016-11-30

Applicant: ADAMA AGAN LTD.

Inventor： Omer TZOR ,  Michael GRABARNICK

IPC: C07D261/08

CPC classification number: C07D261/08

Abstract: A process for preparing isoxaflutole of formula (I) wherein the process comprises: admixing (5-cyclopropyl-4-isoxazolyl)[2-(methylthio)-4-(trifluoromethyl)phenyl]-methanone of formula (II) with acetic acid and hydrogen peroxide in the presence of a strong acid.

公开(公告)号：US20160251323A1

公开(公告)日：2016-09-01

申请号：US15029063

申请日：2014-10-13

Applicant: ADAMA AGAN LTD.

Inventor： Omer TZOR ,  Michael GRABARNICK

IPC: C07D261/08

CPC classification number: C07D261/08

Abstract: A process for preparing isoxaflutole of formula (I) wherein the process comprises: admixing (5-cyclopropyl-4-isoxazolyl)[2-(methylthio)-4-(trifluoromethyl)phenyl]-methanone of formula (II) with acetic acid, acetic anhydride and hydrogen peroxide in the presence of a strong acid.

Abstract translation: 制备式（I）的异构肟基的方法，其中该方法包括：将式（II）的（5-环丙基-4-异恶唑基）[2-（甲硫基）-4-（三氟甲基）苯基] - 甲酮与乙酸混合， 乙酸酐和过氧化氢在强酸存在下进行。