公开(公告)号：US11505576B2

公开(公告)日：2022-11-22

申请号：US16977625

申请日：2019-03-12

Applicant: AFFIBODY AB

Inventor： Caroline Ekblad ,  Elin Gunneriusson ,  Sophia Hober ,  Sarah Lindbo

IPC: C07K14/00 ,  C07K1/14 ,  C12N15/10

Abstract: The disclosure provides a population of polypeptide variants based on a common scaffold, each polypeptide in the population comprising the scaffold amino acid sequence Xsc1AELDXsc2Xsc3GVG AXXIKXIXsc4XA XXVEXVQXXK QXILAX. The disclosure also provides methods for selecting and identifying polypeptides from the population, as well as such polypeptides themselves.

公开(公告)号：US20210047372A1

公开(公告)日：2021-02-18

申请号：US16977625

申请日：2019-03-12

Applicant: AFFIBODY AB

Inventor： Caroline Ekblad ,  Elin Gunneriusson ,  Sophia Hober ,  Sarah Lindbo

IPC: C07K14/00 ,  C07K1/14 ,  C12N15/10

Abstract: The disclosure provides a population of polypeptide variants based on a common scaffold, each polypeptide in the population comprising the scaffold amino acid sequence Xsc1AELDXsc2Xsc3GVG AXXIKXIXsc4XA XXVEXVQXXK QXILAX. The disclosure also provides methods for selecting and identifying polypeptides from the population, as well as such polypeptides themselves.