公开(公告)号：US20160000757A1

公开(公告)日：2016-01-07

申请号：US14789928

申请日：2015-07-01

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Lang Zhuo ,  Chunyan Zhang ,  Yugen Zhang ,  Jackie Y. Ying ,  Began Gopalan ,  Zhiyuan Ke ,  Zhaobing Ding

IPC: A61K31/4178

CPC classification number: A61K31/4178 ,  A61K31/4184 ,  A61K31/4188 ,  A61K31/439 ,  A61K31/4439 ,  C07D233/58 ,  C07D233/60 ,  C07D233/61 ,  C07D235/06 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D471/04 ,  C07D487/04 ,  C07D487/22

Abstract: There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts.

Abstract translation: 目前提供了将抗纤维化或抗癌剂递送至细胞的方法。 所述方法包括使细胞与本文所述的有效量的咪唑鎓和咪唑啉化合物接触，包括咪唑鎓和咪唑啉鎓盐。

公开(公告)号：US20160331727A9

公开(公告)日：2016-11-17

申请号：US14789928

申请日：2015-07-01

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Lang Zhuo ,  Chunyan Zhang ,  Yugen Zhang ,  Jackie Y. Ying ,  Began Gopalan ,  Zhiyuan Ke ,  Zhaobing Ding

IPC: A61K31/4178

CPC classification number: A61K31/4178 ,  A61K31/4184 ,  A61K31/4188 ,  A61K31/439 ,  A61K31/4439 ,  C07D233/58 ,  C07D233/60 ,  C07D233/61 ,  C07D235/06 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D471/04 ,  C07D487/04 ,  C07D487/22

Abstract: There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts.