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公开(公告)号：US09249148B2
公开(公告)日：2016-02-02
申请号：US14422191
申请日：2013-08-16
发明人： Steffen Wildum , Burkhard Klenke , Astrid Wendt
IPC分类号： C07D403/02 , C07D487/04 , A61K31/4745 , C07D471/04 , C07D401/14 , C07D403/04
CPC分类号： C07D487/04 , A61K31/4745 , C07D401/14 , C07D403/04 , C07D471/04
摘要： The present invention relates to new tri(hetero)aryl pyrazoles, methods for their preparation, their use for treating and/or preventing diseases as well as their use in the preparation of drugs for treating and/or preventing diseases, in particular retroviral diseases in humans and/or animals.
摘要翻译： 本发明涉及新的三（杂）芳基吡唑，其制备方法，其用于治疗和/或预防疾病的用途及其在制备用于治疗和/或预防疾病的药物中的用途，特别是用于治疗和/ 人类和/或动物。
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2.发明授权公开(公告)号：US09782390B2
公开(公告)日：2017-10-10
申请号：US15382986
申请日：2016-12-19
发明人： Burkhard Klenke , Irith Wiegand , Guido Schiffer , Heike Broetz-Oesterhelt , Samarendra N. Maiti , Jehangir Khan , Andhe Reddy , Zhixiang Yang , Mostafa Hena , Guofeng Jia , Ou Ligong , Hong Liang , Judy Yip , Chuanjun Gao , Sabiha Tajammul , Rahim Mohammad , Ganguli Biswajeet
IPC分类号： A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/501 , A61K31/497 , A61K31/433 , A61K31/496 , A61K31/506 , A61K45/06
CPC分类号： A61K31/427 , A61K31/4178 , A61K31/433 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06 , C07D417/12 , C07D417/14 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481
摘要： The present invention relates to novel β-lactam compounds, their preparation and use. In particular, this invention relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation.
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3.发明授权Amidine substituted β-lactam compounds, their preparation and use as antibacterial agents 有权氨基取代的β-内酰胺化合物，其制备和用作抗菌剂公开(公告)号：US09556165B2
公开(公告)日：2017-01-31
申请号：US14374325
申请日：2013-01-23
发明人： Burkhard Klenke , Irith Wiegand , Guido Schiffer , Heike Broetz-Oesterhelt , Samarendra N. Maiti , Jehangir Khan , Andhe Reddy , Zhixiang Yang , Mostafa Hena , Guofeng Jia , Ou Ligong , Hong Liang , Judy Yip , Chuanjun Gao , Sabiha Tajammul , Rahim Mohammad , Ganguli Biswajeet
IPC分类号： A61K31/433 , C07D417/14 , A61K31/427 , C07D417/12 , A61K31/4178 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06
CPC分类号： A61K31/427 , A61K31/4178 , A61K31/433 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06 , C07D417/12 , C07D417/14 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481
摘要： The present invention relates to novel β-lactam compounds, their preparation and use. In particular, this invention relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation.
摘要翻译： 本发明涉及新型β-内酰胺化合物，其制备和应用。 特别地，本发明涉及可用作抗微生物剂的脒取代的单内酰胺衍生物及其制备的新型β-内酰胺化合物。
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公开(公告)号：US20150203500A1
公开(公告)日：2015-07-23
申请号：US14422191
申请日：2013-08-16
发明人： Steffen Wildum , Burkhard Klenke , Astrid Wendt
IPC分类号： C07D487/04 , C07D403/04 , C07D401/14 , C07D471/04
CPC分类号： C07D487/04 , A61K31/4745 , C07D401/14 , C07D403/04 , C07D471/04
摘要： The present invention relates to new tri(hetero)aryl pyrazoles, methods for their preparation, their use for treating and/or preventing diseases as well as their use in the preparation of drugs for treating and/or preventing diseases, in particular retroviral diseases in humans and/or animals.
摘要翻译： 本发明涉及新的三（杂）芳基吡唑，其制备方法，其用于治疗和/或预防疾病的用途及其在制备用于治疗和/或预防疾病的药物中的用途，特别是用于治疗和/ 人类和/或动物。
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公开(公告)号：US20150105388A1
公开(公告)日：2015-04-16
申请号：US14361126
申请日：2012-11-29
发明人： Steffen Wildum , Burkhard Klenke , Astrid Wendt
IPC分类号： C07D401/04 , A61K31/4439 , A61K31/5377 , A61K31/496 , C07D417/14 , C07D401/14 , A61K45/06
CPC分类号： C07D401/04 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D417/14
摘要： This invention relates to new carboxamide-substituted heteroaryl-pyrazoles, method for their production, their use for the treatment and/or prophylaxis of diseases, as well as their use for the production of pharmaceutical agents for the treatment and/or prophylaxis of diseases, in particular retroviral diseases, in humans and/or animals.
摘要翻译： 本发明涉及新的羧酰胺取代的杂芳基 - 吡唑，其制备方法，它们用于治疗和/或预防疾病的用途，以及它们用于生产用于治疗和/或预防疾病的药剂的用途， 特别是在人和/或动物中的逆转录病毒疾病。
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公开(公告)号：US09296720B2
公开(公告)日：2016-03-29
申请号：US14361126
申请日：2012-11-29
发明人： Steffen Wildum , Burkhard Klenke , Astrid Wendt
IPC分类号： A61K31/4439 , A61K31/496 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D417/14 , A61K45/06
CPC分类号： C07D401/04 , A61K31/4439 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D417/14
摘要： This invention relates to new carboxamide-substituted heteroaryl-pyrazoles, method for their production, their use for the treatment and/or prophylaxis of diseases, as well as their use for the production of pharmaceutical agents for the treatment and/or prophylaxis of diseases, in particular retroviral diseases, in humans and/or animals.
摘要翻译： 本发明涉及新的羧酰胺取代的杂芳基 - 吡唑，其制备方法，它们用于治疗和/或预防疾病的用途，以及它们用于生产用于治疗和/或预防疾病的药剂的用途， 特别是在人和/或动物中的逆转录病毒疾病。
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7.发明申请AMIDINE SUBSTITUTED BETA-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS 有权氨基替代的BETA-LACTAM化合物，其制备和用作抗菌剂公开(公告)号：US20150045340A1
公开(公告)日：2015-02-12
申请号：US14374325
申请日：2013-01-23
发明人： Burkhard Klenke , Irith Wiegand , Guido Schiffer , Heike Broetz-Oesterhelt , Samarendra N. Maiti , Jehangir Khan , Andhe Reddy , Zhixiang Yang , Mostafa Hena , Guofeng Jia , Ou Ligong , Hong Liang , Judy Yip , Chuanjun Gao , Sabiha Tajammul , Rahim Mohammad , Ganguli Biswajeet
IPC分类号： C07D417/14 , A61K31/427 , A61K45/06 , A61K31/4439 , A61K31/506 , A61K31/501 , A61K31/497 , A61K31/433 , A61K31/496 , C07D417/12 , A61K31/454
CPC分类号： A61K31/427 , A61K31/4178 , A61K31/433 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K45/06 , C07D417/12 , C07D417/14 , Y02A50/473 , Y02A50/475 , Y02A50/478 , Y02A50/481
摘要： The present invention relates to novel β-lactam compounds, their preparation and use. In particular, this invention relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation.
摘要翻译： 本发明涉及新颖的β-内酰胺化合物，其制备和用途。 特别地，本发明涉及可用作抗微生物剂的脒取代的单内酰胺衍生物及其制备的新颖的β-内酰胺化合物。
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