公开(公告)号：US20200239593A1

公开(公告)日：2020-07-30

申请号：US16733376

申请日：2020-01-03

Applicant: AIMM THERAPEUTICS B.V.

Inventor： Hergen SPITS ,  Tim BEAUMONT ,  Marijn Aletta GILLISSEN ,  Adrianus Quirinus BAKKER ,  Mette Deborah HAZENBERG ,  Martijn KEDDE

IPC: C07K16/30 ,  C07K16/06 ,  A61K47/68 ,  C07K16/40 ,  C12P21/00 ,  G01N33/574

Abstract: The invention provides human AML-specific binding compounds that are able to bind a cell surface component of AML cells. Therapeutic uses of binding compounds against AML are also provided.

公开(公告)号：US20160326261A1

公开(公告)日：2016-11-10

申请号：US15105076

申请日：2014-12-17

Applicant: AIMM THERAPEUTICS B.V.

Inventor： Hergen SPITS ,  Tim BEAUMONT ,  Marijn Aletta GILLISSEN ,  Adrianus Quirinus BAKKER ,  Mette Deborah Hazenberg

IPC: C07K16/30 ,  G01N33/574 ,  C12P21/00 ,  A61K47/48 ,  C07K16/40

Abstract: The invention provides human AML-specific binding compounds that are able to bind a cell surface component of AML cells. Therapeutic uses of binding compounds against AML are also provided.

Abstract translation: 本发明提供能够结合AML细胞的细胞表面组分的人类AML特异性结合化合物。 还提供了针对AML的结合化合物的治疗用途。

公开(公告)号：US20180170998A1

公开(公告)日：2018-06-21

申请号：US15737924

申请日：2016-06-24

Applicant: AIMM THERAPEUTICS B.V.

Inventor： Hergen SPITS ,  Marijn Aletta GILLISSEN ,  Martijn KEDDE ,  Mette Deborah HAZENBERG ,  Paula Maria Wilhelmina van HELDEN ,  Wouter POS

IPC: C07K14/705 ,  C07K16/28 ,  G01N33/574

CPC classification number: C07K14/70596 ,  A61K38/00 ,  C07K14/435 ,  C07K16/2896 ,  C07K2317/732 ,  C07K2317/734 ,  G01N33/57426 ,  G01N2333/70596

Abstract: The present invention provides novel compounds comprising an antigen of AML cells, and uses thereof.