公开(公告)号：US10017562B2

公开(公告)日：2018-07-10

申请号：US15638820

申请日：2017-06-30

Applicant: AIMM THERAPEUTICS B.V.

Inventor： Tim Beaumont ,  Etsuko Yasuda

IPC: C07K16/10 ,  G01N33/569 ,  A61K39/00

CPC classification number: C07K16/1027 ,  A61K2039/505 ,  A61K2039/507 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/34 ,  C07K2317/76 ,  G01N33/56983 ,  G01N2333/135

Abstract: The invention relates to human isolated, synthetic or recombinant antibodies or functional parts thereof, specific for the RSV G protein. Antibodies specific for the RSV G protein are particularly suitable for counteracting RSV and symptoms, such as inflammation, resulting from an RSV infection. The invention further relates to the use of such RSV G-specific antibodies for diagnosis of an RSV infection and as a medicament and/or prophylactic agent for at least in part treating or alleviating symptoms of a Respiratory Syncytial Virus infection and/or a Respiratory Syncytial Virus related disorder.

公开(公告)号：US20170342134A1

公开(公告)日：2017-11-30

申请号：US15638820

申请日：2017-06-30

Applicant: AIMM THERAPEUTICS B.V.

Inventor： Tim Beaumont ,  Etsuko Yasuda

IPC: C07K16/10 ,  G01N33/569 ,  A61K39/00

CPC classification number: C07K16/1027 ,  A61K2039/505 ,  A61K2039/507 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/34 ,  C07K2317/76 ,  G01N33/56983 ,  G01N2333/135

Abstract: The invention relates to human isolated, synthetic or recombinant antibodies or functional parts thereof, specific for the RSV G protein. Antibodies specific for the RSV G protein are particularly suitable for counteracting RSV and symptoms, such as inflammation, resulting from an RSV infection. The invention further relates to the use of such RSV G-specific antibodies for diagnosis of an RSV infection and as a medicament and/or prophylactic agent for at least in part treating or alleviating symptoms of a Respiratory Syncytial Virus infection and/or a Respiratory Syncytial Virus related disorder.

公开(公告)号：US09718876B2

公开(公告)日：2017-08-01

申请号：US14359291

申请日：2012-11-16

Applicant: AIMM Therapeutics B.V.

Inventor： Tim Beaumont ,  Etsuko Yasuda

IPC: C07K16/10 ,  G01N33/569 ,  A61K39/00

CPC classification number: C07K16/1027 ,  A61K2039/505 ,  A61K2039/507 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/34 ,  C07K2317/76 ,  G01N33/56983 ,  G01N2333/135

Abstract: The disclosure relates to human isolated, synthetic or recombinant antibodies or functional parts thereof, specific for the RSV G protein. Antibodies specific for the RSV G protein are particularly suitable for counteracting RSV and symptoms, such as inflammation, resulting from an RSV infection. The disclosure further relates to the use of such RSV G-specific antibodies for diagnosis of an RSV infection and as a medicament and/or prophylactic agent for, at least in part, treating or alleviating symptoms of a Respiratory Syncytial Virus infection and/or a Respiratory Syncytial Virus related disorder.

公开(公告)号：US20150004155A1

公开(公告)日：2015-01-01

申请号：US14359291

申请日：2012-11-16

Applicant: AIMM Therapeutics B.V.

Inventor： Tim Beaumont ,  Etsuko Yasuda

IPC: C07K16/10 ,  G01N33/569

CPC classification number: C07K16/1027 ,  A61K2039/505 ,  A61K2039/507 ,  C07K2317/21 ,  C07K2317/30 ,  C07K2317/34 ,  C07K2317/76 ,  G01N33/56983 ,  G01N2333/135

Abstract: The disclosure relates to human isolated, synthetic or recombinant antibodies or functional parts thereof, specific for the RSV G protein. Antibodies specific for the RSV G protein are particularly suitable for counteracting RSV and symptoms, such as inflammation, resulting from an RSV infection. The disclosure further relates to the use of such RSV G-specific antibodies for diagnosis of an RSV infection and as a medicament and/or prophylactic agent for, at least in part, treating or alleviating symptoms of a Respiratory Syncytial Virus infection and/or a Respiratory Syncytial Virus related disorder.

Abstract translation: 本公开涉及对RSV G蛋白特异的人分离的，合成的或重组的抗体或其功能部分。 针对RSV G蛋白特异性的抗体特别适用于抵抗由RSV感染引起的RSV和诸如炎症的症状。 本公开还涉及这样的RSV G特异性抗体用于诊断RSV感染的用途，以及用于至少部分地治疗或缓解呼吸道合胞病毒感染和/或呼吸道合胞病毒感染症状的药物和/或预防剂 呼吸道合胞病毒相关疾病。