公开(公告)号：US12281340B2

公开(公告)日：2025-04-22

申请号：US17025173

申请日：2020-09-18

Applicant: AJINOMOTO CO., INC.

Inventor： Hidemi Nagata ,  Keiko Danjou ,  Jun Takakura ,  Hiroyuki Nozaki

IPC: C12P13/00 ,  C12N9/00 ,  C12N9/42 ,  C12N9/80 ,  C12P21/00

Abstract: A method efficiently produces a compound containing an N-acyl-amino group by an enzymatic method. Specifically, a method of producing a compound containing an N-acyl-amino group includes producing the compound containing an N-acyl-amino group by reacting a compound containing an amino group with a compound containing a carboxyl group in the presence of an enzyme having an ability to bond a carboxyl group and an amino group in an ATP dependent manner to form an amide bond.

公开(公告)号：US20210071214A1

公开(公告)日：2021-03-11

申请号：US17025173

申请日：2020-09-18

Applicant: AJINOMOTO CO., INC.

Inventor： Hidemi Nagata ,  Keiko Danjou ,  Jun Takakura ,  Hiroyuki Nozaki

IPC: C12P13/00 ,  C12P21/00 ,  C12N9/42 ,  C12N9/00 ,  C12N9/80

Abstract: A method efficiently produces a compound containing an N-acyl-amino group by an enzymatic method. Specifically, a method of producing a compound containing an N-acyl-amino group includes producing the compound containing an N-acyl-amino group by reacting a compound containing an amino group with a compound containing a carboxyl group in the presence of an enzyme having an ability to bond a carboxyl group and an amino group in an ATP dependent manner to form an amide bond.