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公开(公告)号：US20230014906A1
公开(公告)日：2023-01-19
申请号：US17816708
申请日：2022-08-01
IPC分类号： C07K14/735 , C07K14/16 , C07K14/73 , C12N15/62 , C07K14/005 , C07K14/72
摘要： Fc-fusion protein derivatives against HIV have enhanced yield in mammalian cells, and extended antiviral and immunomodulatory activities. The Fc-fusion protein derivatives can block the entry of human immunodeficiency virus (HIV) into host cells, elicit effector functions through the activation of natural killer (NK) and other immune system cells, can be produced with high yield in mammalian cells, and have extended activity in vivo. Nucleic acids, vectors and host cells can express the Fc-fusion protein derivatives, which have therapeutic and diagnostic applications in human health.
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2.发明申请公开(公告)号：US20200157192A1
公开(公告)日：2020-05-21
申请号：US16612727
申请日：2018-05-09
IPC分类号： C07K16/10 , A61P31/18 , C12N15/85 , C12N15/62 , G01N33/569 , C07K14/715 , C07K14/73 , C07K14/16
摘要： Fc-fusion protein derivatives against HIV have enhanced yield in mammalian cells, and extended antiviral and immunomodulatory activities. The Fc-fusion protein derivatives can block the entry of human immunodeficiency virus (HIV) into host cells, elicit effector functions through the activation of natural killer (NK) and other immune system cells, can be produced with high yield in mammalian cells, and have extended activity in vivo. Nucleic acids, vectors and host cells can express the Fc-fusion protein derivatives, which have therapeutic and diagnostic applications in human health.
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