公开(公告)号：US20230220443A1

公开(公告)日：2023-07-13

申请号：US16488421

申请日：2018-02-20

Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE

Inventor： Emmanuel Sebastien BURGOS ,  David SHECHTER

IPC: C12Q1/48 ,  G01N21/76 ,  C12Q1/34

CPC classification number: C12Q1/48 ,  C12Y201/01 ,  C12Y305/04 ,  G01N21/76 ,  C12Q1/34

Abstract: Methods and kits are disclosed for measuring activity of a methyltransferase or a radical SAM enzyme or for screening for an inhibitor of a methyltransferase or a radical SAM enzyme, where the methods and kits comprise, respectively, deaminase TM0936 for a MTase coupled assay and deaminase PA3170 for a radical SAM coupled assay.