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公开(公告)号:US10308718B2
公开(公告)日:2019-06-04
申请号:US15867609
申请日:2018-01-10
Applicant: ALECTOR LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas , Robert Pejchal , Anthony B. Cooper
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11339223B2
公开(公告)日:2022-05-24
申请号:US16058817
申请日:2018-08-08
Applicant: ALECTOR LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas , Robert Pejchal , Anthony B. Cooper
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11208488B2
公开(公告)日:2021-12-28
申请号:US16134830
申请日:2018-09-18
Applicant: Alector LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas , Robert Pejchal , Anthony B. Cooper
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11186645B2
公开(公告)日:2021-11-30
申请号:US16741658
申请日:2020-01-13
Applicant: Alector LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas , Robert Pejchal , Anthony B. Cooper
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US12297277B2
公开(公告)日:2025-05-13
申请号:US17836707
申请日:2022-06-09
Applicant: Alector LLC
Inventor: Tina Schwabe , Michael Kurnellas , Arnon Rosenthal , Robert Pejchal , Anthony B. Cooper
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, affinity-matured, humanized antibodies, antibody fragments, etc., that specifically bind a Sortilin protein, e.g., human Sortilin or mammalian Sortilin, and have improved and/or enhanced functional characteristics, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US10428150B2
公开(公告)日:2019-10-01
申请号:US15999627
申请日:2018-08-20
Applicant: Alector LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20190085084A1
公开(公告)日:2019-03-21
申请号:US16134830
申请日:2018-09-18
Applicant: Alector LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20190062433A1
公开(公告)日:2019-02-28
申请号:US16058817
申请日:2018-08-08
Applicant: ALECTOR LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas
IPC: C07K16/28 , A61K31/7088
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US10087255B2
公开(公告)日:2018-10-02
申请号:US15285359
申请日:2016-10-04
Applicant: ALECTOR LLC
Inventor: Arnon Rosenthal , Tina Schwabe , Michael Kurnellas
IPC: A61K39/395 , C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
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