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公开(公告)号：US20200095274A1
公开(公告)日：2020-03-26
申请号：US16591539
申请日：2019-10-02
申请人： ALLERGAN SALES, LLC
IPC分类号： C07J9/00 , A61K31/575
摘要： Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
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公开(公告)号：US11008363B2
公开(公告)日：2021-05-18
申请号：US16856374
申请日：2020-04-23
申请人： ALLERGAN SALES, LLC
发明人： Achampeta Rathan Prasad , Roy A. Swaringen, Jr. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
摘要： Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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公开(公告)号：US10981946B2
公开(公告)日：2021-04-20
申请号：US16591539
申请日：2019-10-02
申请人： ALLERGAN SALES, LLC
摘要： Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
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公开(公告)号：US10472384B2
公开(公告)日：2019-11-12
申请号：US15990135
申请日：2018-05-25
申请人： ALLERGAN SALES LLC
摘要： Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
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公开(公告)号：US20200317716A1
公开(公告)日：2020-10-08
申请号：US16856374
申请日：2020-04-23
申请人： ALLERGAN SALES, LLC
发明人： Achampeta Rathan Prasad , Roy A. Swaringen, JR. , John Gregory Reid , Robert M. Moriarty , Akhila Kumar Sahoo
摘要： Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
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