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公开(公告)号:US10245318B2
公开(公告)日:2019-04-02
申请号:US15110449
申请日:2015-01-09
申请人: ALPHA-O PEPTIDES AG
发明人: Peter Burkhard , Senthil Kumar Raman , Sara Maria Paulillo , Matteo Piazza , Caroline Kulangara , Christian Mittelholzer
IPC分类号: A61K39/39 , A61K39/00 , A61K39/015 , C07K14/195
摘要: The present invention relates to self-assembling protein nanoparticles constructed from suitable oligomerization domains and further incorporating the TLR5 binding protein flagellin as an adjuvant molecule. Furthermore, the invention relates to the use of such nanoparticles for vaccination.