公开(公告)号：US20220010324A1

公开(公告)日：2022-01-13

申请号：US17337161

申请日：2021-06-02

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Sreepriya PRAMOD ,  Marcos Fernando de GODOY LUSSO ,  Jesse FREDERICK ,  Andrew ADAMS ,  Dongmei XU

IPC: C12N15/82

Abstract: The present disclosure provides tobacco having genetic modification(s) in a group of ERF genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.