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公开(公告)号：US20220064610A1
公开(公告)日：2022-03-03
申请号：US17299000
申请日：2019-12-09
Applicant: AMGEN INC.
Inventor： Neeraj J. AGRAWAL , Kristine M. DARIS , Jennitte L. STEVENS , Huong Thi Ngoc LE , Noelia Blanco TALAVAN
IPC: C12N9/12 , C12N15/85 , C07K14/725 , C12N15/90 , A61K35/17
Abstract: PiggyBac transposases engineered to increase stability in a cell. The engineered piggyBac transposases are useful for stably transforming cells, cell line development, genome modification, and improving titer of recombinant proteins, among other uses.
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