公开(公告)号：US20170190739A1

公开(公告)日：2017-07-06

申请号：US15300209

申请日：2015-04-03

Applicant: AMGEN INC.

Inventor： Jeroen BEZEMER ,  Ying CHEN ,  Richard CROCKETT ,  Kevin CROSSLEY ,  Sheng CUI ,  Liang HUANG ,  Sian JONES ,  Asher LOWER ,  Krishnakumar RANGANATHAN

IPC: C07K7/06 ,  C07K1/107

CPC classification number: C07K7/06 ,  A61K38/00 ,  C07K1/1075

Abstract: A method for preparing AMG 416, or a pharmaceutically acceptable salt thereof, is provided. AMG 416 is a synthetic, eight amino-acid selective peptide agonist of the calcium sensing receptor. It is being developed as an intravenous treatment of secondary hyperparathyroidism (SHPT) in hemodialysis patients with chronic kidney disease—mineral and bone disorder (CKD-MBD).

公开(公告)号：US20230099078A1

公开(公告)日：2023-03-30

申请号：US17852263

申请日：2022-06-28

Applicant: AMGEN INC.

Inventor： Jeroen BEZEMER ,  Ying CHEN ,  Richard CROCKETT ,  Kevin CROSSLEY ,  Sheng CUI ,  Liang HUANG ,  Sian JONES ,  Asher LOWER ,  Krishnakumar RANGANATHAN

IPC: C07K7/06 ,  C07K1/107

Abstract: A method for preparing AMG 416, or a pharmaceutically acceptable salt thereof, is provided.

公开(公告)号：US20190352336A1

公开(公告)日：2019-11-21

申请号：US16532344

申请日：2019-08-05

Applicant: AMGEN INC.

Inventor： Jeroen BEZEMER ,  Ying CHEN ,  Richard CROCKETT ,  Kevin CROSSLEY ,  Sheng CUI ,  Liang HUANG ,  Sian JONES ,  Asher LOWER ,  Krishnakumar RANGANATHAN

IPC: C07K7/06 ,  C07K1/107

Abstract: A method for preparing AMG 416, or a pharmaceutically acceptable salt thereof, is provided.