公开(公告)号：US20140227779A1

公开(公告)日：2014-08-14

申请号：US14346995

申请日：2012-09-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Gyung Cho ,  Bum Ho Bin ,  Tae Ryong Lee ,  Ji Yeon Han ,  Hyun Jung Choi

IPC: C12N5/071

CPC classification number: C12N5/0626 ,  C12N2500/14 ,  C12N2506/094

Abstract: The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.

Abstract translation: 本发明涉及新型黑素细胞和黑素细胞。 此外，本发明涉及一种生产黑素细胞和黑素细胞的新方法。 具体而言，提供基因表达，黑色素含量和酪氨酸酶活性与常规黑素细胞不同的新型黑素细胞。 更具体地说，提供了基因表达，黑色素含量，酪氨酸酶活性和蛋白质表达与常规黑素细胞不同的新型黑素细胞。 另外，提供了通过培养角质形成细胞产生黑素细胞或黑素细胞的新方法。

公开(公告)号：US10344260B2

公开(公告)日：2019-07-09

申请号：US14346995

申请日：2012-09-27

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Gyung Cho ,  Bum Ho Bin ,  Tae Ryong Lee ,  Ji Yeon Han ,  Hyun Jung Choi

IPC: C12N5/071

Abstract: The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.