公开(公告)号：US10111856B2

公开(公告)日：2018-10-30

申请号：US14888623

申请日：2014-05-07

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Jung Shin ,  Hyun Woo Jeong ,  Ji Hae Lee ,  Dae Jin Min ,  Dae Bang Seo ,  Sang Jun Lee

IPC: A61K31/37 ,  A61K36/48

Abstract: The present invention relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a soybean extract comprising coumestrol as an active ingredient, and more specifically relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a germinated and fermented soybean extract comprising coumestrol as an active ingredient.

公开(公告)号：US10959981B2

公开(公告)日：2021-03-30

申请号：US15989544

申请日：2018-05-25

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyun Jung Shin ,  Hyun Woo Jeong ,  Ji Hae Lee ,  Dae Jin Min ,  Dae Bang Seo ,  Sang Jun Lee

IPC: A61K31/37 ,  A61K36/48

Abstract: The present invention relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a soybean extract comprising coumestrol as an active ingredient, and more specifically relates to a composition for, inter alia, preventing or treating a climacteric disease, or preventing or improving a climacteric skin symptom comprising a germinated and fermented soybean extract comprising coumestrol as an active ingredient.

公开(公告)号：US10669527B2

公开(公告)日：2020-06-02

申请号：US15562576

申请日：2016-03-22

Applicant: AMOREPACIFIC CORPORATION ,  SOONGSIL UNIVERSITY RESEARCH CONSORTIUM TECHNO-PARK

Inventor： Dae Jin Min ,  Sung Hoon Lee ,  Hae Kwang Lee ,  Jae Hyun Jeong ,  Hee Wook Ryu ,  Hee Jin Kim

IPC: C12M1/32 ,  C12N5/071 ,  C12M3/00 ,  A61K35/36 ,  A61L27/24 ,  A61L27/60 ,  C12M3/04

Abstract: An artificial skin culture container according to the present invention can solve the problems of the contraction of the dermal layer of artificial skin and the detachment thereof from the culture container, which result from an interaction between collagen and fibroblasts existing in the dermal layer of artificial skin during the production of the artificial skin, by using agar and hydrophobically modifying a portion of the agar. Therefore, the use of the culture container enables to stably culture artificial skin and produce artificial skin similar to the human skin. In addition, the artificial skin culture container of the present invention comprises agar, and thus a culture solution can be supplied through a side portion as well as a lower portion of the culture container, which allows to effectively culture artificial skin.