公开(公告)号：US12017974B2

公开(公告)日：2024-06-25

申请号：US17418940

申请日：2020-01-03

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yunghyup Joo ,  Jaeyoung Ko ,  Jaewon You ,  Yong Jin Kim ,  Tae Ryong Lee

IPC: C07C233/60 ,  A61K8/42 ,  A61K9/00 ,  A61Q19/02 ,  C07C231/02

CPC classification number: C07C233/60 ,  A61K8/42 ,  A61K9/0014 ,  A61Q19/02 ,  C07C231/02 ,  A61K2800/43

Abstract: The present specification relates to an adamantanecarboxylic acid benzyl amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, and a skin whitening composition comprising the same as an active ingredient. Specifically, the compound, according to the present specification, is a compound having a novel structure having adamantanecarboxylic acid bound to an amine compound, and exhibits a skin whitening effect by inhibiting the production of melanin, and thus may be used in various ways as a pharmaceutical composition, a cosmetic composition or a skin preparation for external use.