专利检索 ap:("ANDREW BEATON" OR "PETER FRANZ ERTL" OR "GERALD WAYNE GOUGH" OR "ANDREW LEAR" OR "JOHN PHILIP TITE" OR "CATHERINE ANN VAN WELY") AND inv:"ANDREW BEATON" 第 1 页

1.

发明申请
HIV-GAG CODON-OPTIMISED DNA VACCINES 审中-公开
标题翻译： HIV-GAG CODON-OPTIMIZED DNA VACCINES

公开(公告)号：US20090203144A1

公开(公告)日：2009-08-13

申请号：US12015756

申请日：2008-01-17

申请人： ANDREW BEATON , PETER FRANZ ERTL , GERALD WAYNE GOUGH , ANDREW LEAR , JOHN PHILIP TITE , CATHERINE ANN VAN WELY

发明人： ANDREW BEATON , PETER FRANZ ERTL , GERALD WAYNE GOUGH , ANDREW LEAR , JOHN PHILIP TITE , CATHERINE ANN VAN WELY

IPC分类号： A61K31/7052 , C07H21/00 , C12N15/63 , C07K14/16 , A61P31/18

CPC分类号： A61K39/21 , A61K39/12 , A61K2039/53 , A61K2039/545 , A61K2039/57 , C07K14/005 , C07K2319/00 , C12N2740/16222 , C12N2740/16234 , C12N2740/16322 , C12N2740/16334

摘要： The invention provides a nucleotide sequence that encodes an HIV-1 gag protein or fragment thereof containing a gag epitope and a second HIV antigen or a fragment encoding an epitope of said second HIV antigen, operably linked to a heterologous promoter. Preferred polynucleotide sequences further encodes nef or a fragment thereof and RT or a fragment thereof.

摘要翻译： 本发明提供编码HIV-1gag蛋白或其片段的核苷酸序列，其含有gag表位和第二HIV抗原或编码所述第二HIV抗原表位的片段，其可操作地连接到异源启动子。优选的多核苷酸序列进一步编码nef或其片段和RT或其片段。