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公开(公告)号：US20220389499A1
公开(公告)日：2022-12-08
申请号：US17728087
申请日：2022-04-25
发明人： Willy K. Wiyatno , Linda Lee , David Cox , James Nurse , Douglas Greiner , Dennis Lehto , Janusz Wojtowicz , Sam Woo , Richard Reel
IPC分类号： C12Q1/6869 , B01L3/00 , F15C5/00 , F16K99/00 , G01N35/08 , G01N1/14 , C12Q1/6806 , C12Q1/6874 , G01N27/447
摘要： A method for forming discrete volumes of aqueous fluid may comprise flowing aqueous fluid into a first conduit from a supply of aqueous fluid and flowing into the first conduit a spacing liquid supplied from a second conduit, the spacing liquid being immiscible with the aqueous fluid. The flowing of the aqueous fluid and the spacing liquid into the first conduit forms discrete volumes of the aqueous fluid, with consecutive discrete volumes of the aqueous fluid separated by the spacing liquid. The method may further comprise transferring the discrete volumes of the aqueous fluid and spacing liquid from the first conduit to a third conduit for processing.
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公开(公告)号：US11319585B2
公开(公告)日：2022-05-03
申请号：US16655911
申请日：2019-10-17
发明人： Willy K. Wiyatno , Linda Lee , David Cox , James Nurse , Douglas Greiner , Dennis Lehto , Janusz Wojtowicz , Sam Woo , Richard Reel
IPC分类号： G01N1/14 , G01N35/08 , G01N27/447 , C12Q1/6869 , C12Q1/6806 , C12Q1/6874 , B01L3/00 , F15C5/00 , F16K99/00 , B01L3/02 , B01L7/00
摘要： A system may include a first conduit configured to form a first batch of discrete volumes of aqueous fluid separated by spacing liquid disposed between consecutive volumes of aqueous fluid, the spacing liquid being immiscible with the aqueous fluid volumes; a second conduit, fluidically coupled to the first conduit, the second conduit configured to statically hold the first batch of discrete volumes of aqueous fluid; and a third conduit configured to receive the first batch of discrete volumes of aqueous fluid from the second conduit. The third conduit can be configured to transfer the discrete volumes of aqueous fluid of the first batch for downstream processing.
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