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公开(公告)号:US20240077481A1
公开(公告)日:2024-03-07
申请号:US18280340
申请日:2022-03-03
申请人: ARES TRADING S.A.
IPC分类号: G01N33/569 , G01N33/564
CPC分类号: G01N33/56972 , G01N33/564 , G01N2800/285 , G01N2800/52 , G01N2800/54
摘要: The invention pertains to improved treatment methods using DMDS, in particular cladribine, for the treatment of autoimmune diseases, in particular multiple sclerosis, and biomarkers, in particular immune cell subtypes, for predicting and/or optimising said treatment methods. The methods described rely on the use of immune cell subtypes, in particular T cells, B cells, NK cells subtypes and their ratios as present in blood samples from the patients for predicting and/or optimising the use of cladribine in the treatment of multiple sclerosis.