公开(公告)号：US20240335122A1

公开(公告)日：2024-10-10

申请号：US18696528

申请日：2022-09-26

Applicant: ARISTOTLE UNIVERSITY OF THESSALONIKI - ELKE

Inventor： Theodoros KARAPANTSIOS ,  Konstantinos ZACHARIAS ,  Sotiris EVGENIDIS

IPC: A61B5/02 ,  A61B5/00 ,  A61B5/053 ,  G16H50/30

CPC classification number: A61B5/02007 ,  A61B5/0053 ,  A61B5/053 ,  A61B5/725 ,  A61B5/726 ,  A61B5/742 ,  G16H50/30

Abstract: A method for determining a vascular endothelium functionality of an artery of a person, the method comprising: acquiring measurement data associated with a series of electrical measurements taken by an electrical impedance spectroscopy device; extracting an impedance time series associated with the impedance changes of the of the medium intervening between each pair of electrodes; filtering the impedance time series in the frequency domain to extract at least a low pass frequency, LPF, and a band limited frequency, BPF, component waveforms for each pair of electrodes; processing the LPF and BPF component waveforms obtained from each pair of electrodes to extract a set of biomarker parameter values, each biomarker parameter being indicative of a particular aspect of the endothelium functionality of the artery of the person; and determining an endothelium functionality index indicative of the vascular endothelium functionality of the artery of the person.