公开(公告)号：US20160153991A1

公开(公告)日：2016-06-02

申请号：US14776434

申请日：2014-03-12

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Nidhi GUPTA ,  Chris DIEHNELT ,  Charles ARNTZEN ,  Stephen JOHNSTON

IPC: G01N33/569 ,  C07K14/00

CPC classification number: G01N33/56983 ,  C07K14/001 ,  C07K16/08 ,  C07K2318/20 ,  G01N2333/08 ,  G01N2469/10 ,  G01N2800/26

Abstract: Synbodies specific for Norovirus and coupled with a substrate provide Norovirus binding and detection platforms (FIG. 1). A Norovirus capturing platform, comprising one or more synbodies selected from the group consisting of synbodies 6-6, 92-92, 93-93, and 94-94 coupled to a substrate, has been found to found to bind with either GII.4 Minerva or both GII.4 Minerva and GII.4 Sydney# strains of norovirus.

Abstract translation: 针对诺如病毒特异性并与底物偶联的合成体提供诺如病毒结合和检测平台（图1）。 已经发现包含一个或多个选自偶联于底物的合成体6-6,92-92,93-93和94-94的合成体的诺如病毒捕获平台被发现与GII.4结合 Minerva或GII.4 Minerva和GII.4悉尼＃诺如病毒株。