公开(公告)号：US20220333216A1

公开(公告)日：2022-10-20

申请号：US17616341

申请日：2020-06-03

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY ,  EMORY UNIVERSITY

Inventor： Sidney HECHT ,  Jesse WAGGONER ,  Mingxuan GAO ,  Shengxi CHEN

IPC: C12Q1/70 ,  C12Q1/6818

Abstract: Described herein are systems and methods that may be used to differentially detect viral serotype specific nucleic acid. For example, these systems may comprise multiple DNA-nanostructures, capture oligonucleotides and protector oligonucleotides, wherein each DNA-nanostructure and its associated capture oligonucleotide and protector oligonucleotide are specific for a unique viral type or serotype.

公开(公告)号：US20180360647A1

公开(公告)日：2018-12-20

申请号：US15771377

申请日：2016-10-28

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Shengxi CHEN

IPC: A61F6/04 ,  A61F5/41 ,  A61K33/00 ,  A61K9/00 ,  A61K31/7056 ,  A61K9/70

Abstract: A condom assembly includes at least one of a condom, patch or glove made of at least one of natural latex, synthetic latex or the mixture of natural latex and synthetic latex. The natural latex, synthetic latex or the mixture of natural latex and synthetic latex contain prodrugs of nitric oxide and/or other active ingredients.

公开(公告)号：US20190282706A1

公开(公告)日：2019-09-19

申请号：US16301888

申请日：2017-05-08

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Shengxi CHEN ,  Yanmin ZHANG ,  Sidney HECHT

IPC: A61K47/68 ,  A61K38/16 ,  C07K14/31 ,  C07K16/30 ,  C07K16/32

Abstract: Provided herein are therapeutic agents having specificity for having inhibitory activity against cancer cells that overexpress human epidermal growth factor receptor (HER) genes, including therapeutic agents comprising one or more HER-targeting peptides, pharmaceutical compositions comprising such therapeutic agents, and methods of using such compositions to treat or prevent a cancer or other disease condition associated with HER overexpression.

公开(公告)号：US20210121319A1

公开(公告)日：2021-04-29

申请号：US17092855

申请日：2020-11-09

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Shengxi CHEN

IPC: A61F6/04 ,  A61F5/41 ,  B32B27/04 ,  C08K3/20 ,  B32B27/40 ,  A61K9/00 ,  A61K9/70 ,  A61K31/7056 ,  A61K33/00

Abstract: A condom apparatus including at least one of a condom containing a compound of Formula 1 wherein the condom is configured to deliver one or more active ingredients selected from the group consisting of arginine, a vasodilator, nitrates, an ergot alkaloid, a long acting alpha-adrenoceptor blocker, a short acting alpha-adrenoceptor blocker, an anti-hypertensive, a prostaglandin, and a phosphodiesterase inhibitor is disclosed.

公开(公告)号：US20210052415A1

公开(公告)日：2021-02-25

申请号：US17090543

申请日：2020-11-05

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Shengxi CHEN

IPC: A61F6/04 ,  A61F5/41 ,  B32B27/04 ,  C08K3/20 ,  B32B27/40 ,  A61K9/00 ,  A61K9/70 ,  A61K31/7056 ,  A61K33/00

Abstract: A method to enhance a male erection or female arousal in a mammal includes topically administering a compound of Formula 1 to the mammal.