公开(公告)号：US20240408194A1

公开(公告)日：2024-12-12

申请号：US18701892

申请日：2022-10-20

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Nicholas Stephanopoulos ,  Yang Xu ,  Petr Sulc ,  Hao Yan ,  Rong Zheng

IPC: A61K39/215 ,  A61K39/00 ,  A61K39/385 ,  A61P37/04 ,  B82Y5/00

Abstract: The present disclosure relates to DNA nanocarriers and methods of use for stimulating an immune response in a host. In some embodiments, the DNA nanocarriers comprise SARS-CoV-2 surface glycoprotein.

公开(公告)号：US20240409669A1

公开(公告)日：2024-12-12

申请号：US18701901

申请日：2022-10-20

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Nicholas Stephanopoulos ,  Yang Xu ,  Petr Sulc ,  Hao Yan ,  Rong Zheng ,  Abhay Prasad

IPC: C07K19/00 ,  A61K38/00 ,  A61P31/14 ,  C07K14/005

Abstract: The present disclosure relates to DNA-peptide hybrid molecules. In some embodiments, the DNA-peptide hybrid molecules comprise target-specific binding peptides which selectively bind to SARS-COV-2 surface glycoprotein. Methods of using DNA-peptide hybrid molecules in the treatment of SARS-COV-2 infection are also provided.