公开(公告)号：US20160025702A1

公开(公告)日：2016-01-28

申请号：US14775360

申请日：2014-03-12

申请人： ARIZONA BOARD OF REGENTS on behalf of Arizona STATE UNIVERSITY

发明人： Stuart LINDSAY ,  Brett GYARFAS ,  Predrag KRSTIC ,  Padmini KRISHNAKUMAR

IPC分类号： G01N33/487

CPC分类号： G01N33/48721 ,  C12Q1/6869 ,  G01N15/1031 ,  G01N15/1056 ,  G01N2015/0038 ,  C12Q2565/631

摘要： Some embodiments of the present disclosure are directed to systems, methods and devices for controlling the transit of a molecule across a nanopore. Some embodiments are directed to a device comprising a first compartment, a second compartment, a first pair of electrodes comprising a first electrode provided in the first compartment and a second electrode provided in the second compartment, a partition separating the first compartment from the second compartment, an orifice provided in the partition, a second pair of electrodes arranged proximate the orifice, the second pair of electrodes being functionalized with molecules, and a tunnel gap comprising the spacing between the second pair of electrodes.

摘要翻译： 本公开的一些实施方案涉及用于控制分子跨越纳米孔的转运的系统，方法和装置。 一些实施例涉及包括第一隔室，第二隔室，包括设置在第一隔室中的第一电极和设置在第二隔室中的第二电极的第一对电极的设备，将第一隔室与第二隔室分开的隔板 ，设置在隔板中的孔口，邻近孔口布置的第二对电极，第二对电极用分子功能化，以及包括第二对电极间的间隔的隧道间隙。