公开(公告)号：US20160108034A1

公开(公告)日：2016-04-21

申请号：US14855986

申请日：2015-09-16

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Patrick Rene ANGIBAUD ,  Michel OBRINGER ,  Julien Jeremie Joseph MARIN ,  Matthieu JEANTY

IPC: C07D471/04 ,  A61K45/06 ,  A61K31/4545 ,  A61K31/444 ,  A61K31/4375 ,  A61K31/506

CPC classification number: A61K31/4375 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/506 ,  A61K45/06 ,  C07D471/04

Abstract: The invention relates to new naphthyridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract translation: 本发明涉及新的萘啶衍生物化合物，包含所述化合物的药物组合物，用于制备所述化合物的方法以及所述化合物在治疗疾病中的用途。 癌症。

公开(公告)号：US20170105978A1

公开(公告)日：2017-04-20

申请号：US15339148

申请日：2016-10-31

Applicant: ASTEX THERAPEUTICS LIMITED

Inventor： Patrick René ANGIBAUD ,  Michel OBRINGER ,  Julien Jérémie Joseph MARIN ,  Matthieu JEANTY

IPC: A61K31/4375 ,  A61K31/4545 ,  A61K31/444 ,  A61K31/506

CPC classification number: A61K31/4375 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/506 ,  A61K45/06 ,  C07D471/04

Abstract: The invention relates to new naphthyridine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.