公开(公告)号：US20140107696A1

公开(公告)日：2014-04-17

申请号：US14147149

申请日：2014-01-03

申请人： Atritech, Inc.

发明人： Thomas E. Borillo ,  Dean Peterson ,  Gregg S. Sutton ,  Jeffrey Welch

IPC分类号： A61F2/01

CPC分类号： A61F2/013 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/00575 ,  A61F2/01 ,  A61F2002/015 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0069 ,  A61F2230/008

摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

摘要翻译： 用于过滤血流通过心房的口的植入装置具有其中一个或多个可膨胀的部件结构。 具有未膨胀状态的组件结构的装置具有适合于皮内递送至心房附属部位的紧凑尺寸。 可扩展组件结构在现场扩展以部署设备。 装置可以具有足够短的轴向长度，使得装置长度的大部分或几乎全部可以适合于口腔区域。

公开(公告)号：US10278805B2

公开(公告)日：2019-05-07

申请号：US14866017

申请日：2015-09-25

申请人： ATRITECH, INC.

发明人： Thomas E. Borillo ,  Dean Peterson ,  Gregg S. Sutton ,  Jeffrey Welch

IPC分类号： A61F2/06 ,  A61F2/01 ,  A61B17/12 ,  A61B17/00

摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

公开(公告)号：US20160008122A1

公开(公告)日：2016-01-14

申请号：US14866017

申请日：2015-09-25

申请人： ATRITECH, INC.

发明人： Thomas E. Borillo ,  Dean Peterson ,  Gregg S. Sutton ,  Jeffrey Welch

IPC分类号： A61F2/01

CPC分类号： A61F2/013 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/00575 ,  A61F2/01 ,  A61F2002/015 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0069 ,  A61F2230/008

摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

摘要翻译： 用于过滤血流通过心房的口的植入装置具有其中一个或多个可膨胀的部件结构。 具有未膨胀状态的组件结构的装置具有适合于皮内递送至心房附属部位的紧凑尺寸。 可扩展组件结构在现场扩展以部署设备。 装置可以具有足够短的轴向长度，使得装置长度的大部分或几乎全部可以适合于口腔区域。

公开(公告)号：US20160058539A1

公开(公告)日：2016-03-03

申请号：US14845524

申请日：2015-09-04

申请人： ATRITECH INC.

发明人： Robert A. VanTassel ,  Robert G. Hauser ,  Robert Schwartz ,  David Holmes ,  Gregg S. Sutton ,  Thomas E. Borillo ,  Jeffrey Welch

IPC分类号： A61F2/01 ,  A61B17/12 ,  A61B17/00

CPC分类号： A61B17/00234 ,  A61B17/0057 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/00243 ,  A61B2017/00597 ,  A61B2017/00619 ,  A61B2017/00632 ,  A61B2017/1205 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0076 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2230/0093

摘要： Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage.The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.

摘要翻译： 用于永久性放置在患者左心耳的口上的装置，其包括配置成延伸穿过左心耳的口的过滤膜。 过滤膜具有允许血液流过但可以基本上抑制血栓通过的可渗透结构。 该装置还包括附接到过滤膜的支撑结构，其通过永久地接合左心耳内壁的一部分而将过滤膜保持在左心耳的口处的适当位置。 支撑结构可以从第一构型径向扩张到接合左心耳的口或内壁的第二构型。 过滤膜可以限定穿过其中的开口，其被构造成从阻止血栓通过的第一尺寸膨胀到允许介入装置（例如膨胀气囊）穿过其中的第二尺寸，并且其中开口是弹性的 偏向于第一大小。

公开(公告)号：US09161830B2

公开(公告)日：2015-10-20

申请号：US14147149

申请日：2014-01-03

申请人： ATRITECH, INC.

发明人： Thomas E. Borillo ,  Dean A. Peterson ,  Gregg Sutton ,  Jeffrey Welch

IPC分类号： A61M29/00 ,  A61F2/01 ,  A61B17/12 ,  A61B17/00

CPC分类号： A61F2/013 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/00575 ,  A61F2/01 ,  A61F2002/015 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0069 ,  A61F2230/008

摘要： Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

摘要翻译： 用于过滤血流通过心房的口的植入装置具有其中一个或多个可膨胀的部件结构。 具有未膨胀状态的组件结构的装置具有适合于皮内递送至心房附属部位的紧凑尺寸。 可扩展组件结构在现场扩展以部署设备。 装置可以具有足够短的轴向长度，使得装置长度的大部分或几乎全部可以适合于口腔区域。

公开(公告)号：US09132000B2

公开(公告)日：2015-09-15

申请号：US13922024

申请日：2013-06-19

申请人： ATRITECH INC.

发明人： Robert A. VanTassel ,  Robert G. Hauser ,  Robert Schwartz ,  David Holmes ,  Gregg S. Sutton ,  Thomas E. Borillo ,  Jeffrey Welch

IPC分类号： A61M29/00 ,  A61F2/01 ,  A61B17/12 ,  A61B17/00

CPC分类号： A61F2/01 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/00243 ,  A61B2017/00597 ,  A61B2017/00619 ,  A61B2017/00632 ,  A61B2017/1205 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0076 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2230/0093

摘要： Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.

摘要翻译： 用于永久性放置在患者左心耳的口上的装置，其包括配置成延伸穿过左心耳的口的过滤膜。 过滤膜具有允许血液流过但可以基本上抑制血栓通过的可渗透结构。 该装置还包括附接到过滤膜的支撑结构，其通过永久地接合左心耳内壁的一部分而将过滤膜保持在左心耳的口处的适当位置。 支撑结构可以从第一构型径向扩张到接合左心耳的口或内壁的第二构型。 过滤膜可以限定穿过其中的开口，其被构造成从阻止血栓通过的第一尺寸膨胀到允许介入装置例如膨胀气囊通过的第二尺寸，并且其中开口是弹性的 偏向于第一大小。

公开(公告)号：US20140163605A1

公开(公告)日：2014-06-12

申请号：US13922024

申请日：2013-06-19

申请人： ATRITECH INC.

发明人： Robert A. VanTassel ,  Robert G. Hauser ,  Robert Schwartz ,  David Holmes ,  Gregg S. Sutton ,  Thomas E. Borillo ,  Jeffrey Welch

IPC分类号： A61F2/01

CPC分类号： A61F2/01 ,  A61B17/00234 ,  A61B17/0057 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/00243 ,  A61B2017/00597 ,  A61B2017/00619 ,  A61B2017/00632 ,  A61B2017/1205 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0076 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2230/0093

摘要： Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g., an expansion balloon, to pass therethrough, and wherein the opening is resiliently biased towards the first size.

摘要翻译： 用于永久性放置在患者左心耳的口上的装置，其包括配置成延伸穿过左心耳的口的过滤膜。 过滤膜具有允许血液流过但可以基本上抑制血栓通过的可渗透结构。 该装置还包括附接到过滤膜的支撑结构，其通过永久地接合左心耳内壁的一部分而将过滤膜保持在左心耳的口处的适当位置。 支撑结构可以从第一构型径向扩张到接合左心耳的口或内壁的第二构型。 过滤膜可以限定穿过其中的开口，其被构造成从阻止血栓通过的第一尺寸膨胀到允许介入装置例如膨胀气囊通过的第二尺寸，并且其中开口是弹性的 偏向于第一大小。