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公开(公告)号:US20180273477A1
公开(公告)日:2018-09-27
申请号:US15935558
申请日:2018-03-26
发明人: Christian Manfred FRECH , Pasquale Gabriele GRIECO , Christine AEBERSOLD , Patrick MÜLLER , Jan-Erik INGENHOFF , Miriam OBERHOLZER , Viktorya RSTAKYAN , Roman Gerber AESCHBACHER
IPC分类号: C07D213/40
CPC分类号: C07D213/40 , C07D213/56
摘要: The present invention relates to a new route of synthesis to obtain pharmaceutically acceptable Vismodegib. In addition, besides the synthesis also suitable pharmaceutical compositions and the use of the compound for the treatment of basal-cell carcinomas are disclosed.