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公开(公告)号:US20150266977A1
公开(公告)日:2015-09-24
申请号:US14625575
申请日:2015-02-18
Applicant: AbbVie Inc.
Inventor: Chung-Ming Hsieh , Alexander Ivanov , Wendy Waegell , Yulia Kutskova , John Memmott , Lorenzo Benatuil , Jacqueline Bixby , Emma Fung , Sahana Bose , Alyssa Brito
CPC classification number: C07K16/468 , A61K31/353 , A61K31/439 , A61K31/44 , A61K31/4439 , A61K31/519 , A61K31/56 , A61K38/13 , A61K38/1793 , A61K38/18 , A61K38/1808 , A61K38/1816 , A61K38/19 , A61K38/191 , A61K38/2026 , A61K38/2066 , A61K38/2073 , A61K38/217 , A61K39/3955 , A61K2039/505 , C07K16/18 , C07K16/22 , C07K16/241 , C07K2317/21 , C07K2317/31 , C07K2317/565 , C07K2317/60 , C07K2317/64 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: Proteins that bind sclerostin or sclerostin and TNF are described along with there use in composition and methods for treating, preventing, and diagnosing sclerostin related diseases and for detecting sclerostin or sclerostin and TNF in cells, tissues, samples, and compositions.
Abstract translation: 与用于治疗,预防和诊断硬化性相关疾病的组合物和方法一起描述了结合硬化蛋白或硬化性骨肉瘤和TNF的蛋白质,并用于检测细胞,组织,样品和组合物中的硬化蛋白或硬化性骨肉瘤和TNF。