公开(公告)号：US12083227B2

公开(公告)日：2024-09-10

申请号：US16105440

申请日：2018-08-20

Applicant: AbbVie Inc. ,  Neurocrine Biosciences, Inc.

Inventor： Yihong Qiu ,  Yuchuan Gong ,  Alexander Ruggles ,  Jared A. Baird ,  Hui Zu ,  Gregory A. McClelland ,  Anna V. Stepanenko

IPC: A61K9/20 ,  A61K31/513 ,  A61P15/00

CPC classification number: A61K9/2031 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2027 ,  A61K31/513 ,  A61P15/00

Abstract: The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using such compositions. The disclosure also relates to methods of facilitating release of a GnRH antagonist from a pharmaceutical composition.

公开(公告)号：US20190054027A1

公开(公告)日：2019-02-21

申请号：US16105440

申请日：2018-08-20

Applicant: AbbVie Inc.

Inventor： Yihong Qiu ,  Yuchuan Gong ,  Alexander Ruggles ,  Jared A. Baird ,  Kristof Chwalisz ,  Charlotte D. Owens ,  James W. Thomas ,  Jane Castelli-Haley ,  Keith Gordon ,  Michael C. Snabes ,  Ahmed M. Soliman ,  Oscar Antunez Flores ,  Rita Jain ,  Juki Wing-Keung Ng ,  Janine D. North ,  Hannah Palac ,  Paul M. Peloso ,  Laura A. Williams ,  Hui Zu ,  Yuerong Hu

IPC: A61K9/20 ,  A61K31/513 ,  A61P15/00

Abstract: The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using such compositions. The disclosure also relates to methods of facilitating release of a GnRH antagonist from a pharmaceutical composition.