公开(公告)号：US20210130346A1

公开(公告)日：2021-05-06

申请号：US16605039

申请日：2017-04-14

申请人： AbbVie Inc.

发明人： David Hardee ,  Jason Brewer ,  Lisa Hasvold ,  Dachun Liu ,  Keith McDaniel ,  Michael Schrimpf ,  George Sheppard

IPC分类号： C07D471/04 ,  A61P35/04

摘要： Compounds of formula (I), wherein R1, R2, R3, R5, R6, R7, A1, A2, A3, A4, X1, and X2 have any of the values defined in the specification and pharmaceutically acceptable salts thereof, which are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS are provided. Pharmaceutical compositions comprising of compounds of formula (I) are also provided.

公开(公告)号：US20220017511A1

公开(公告)日：2022-01-20

申请号：US17183832

申请日：2021-02-24

申请人： AbbVie Inc.

发明人： Steven D. Fidanze ,  Lisa A. Hasvold ,  Dachun Liu ,  Keith F. McDaniel ,  John Pratt ,  Michael Schrimpf ,  George Sheppard ,  Le Wang ,  Bing Li

IPC分类号： C07D471/04

摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).

公开(公告)号：US20240360124A1

公开(公告)日：2024-10-31

申请号：US18516230

申请日：2023-11-21

申请人： AbbVie Inc.

发明人： Steven D. Fidanze ,  Lisa A. Hasvold ,  Dachun Liu ,  Keith F. McDaniel ,  John Pratt ,  Michael Schrimpf ,  George Sheppard ,  Le Wang ,  Bing Li

IPC分类号： C07D471/04

CPC分类号： C07D471/04

摘要： The present invention provides for compounds of formula (I)




wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).

公开(公告)号：US20200255426A1

公开(公告)日：2020-08-13

申请号：US16858930

申请日：2020-04-27

申请人： AbbVie Inc.

发明人： Steven D. Fidanze ,  Lisa A. Hasvold ,  Dachun Liu ,  Keith F. McDaniel ,  John Pratt ,  Michael Schrimpf ,  George Sheppard ,  Le Wang ,  Bing Li

IPC分类号： C07D471/04

摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).