公开(公告)号：US20170197980A1

公开(公告)日：2017-07-13

申请号：US15321153

申请日：2015-06-25

Applicant: AbbVie Inc.

Inventor： Lloyd S. Dias ,  Rodney James Ketner ,  Jonathan M. Miller ,  Warren Kenyon Miller ,  Michael Mark Morgen ,  Brice George Murri ,  David Thomas Vodak

IPC: C07D495/04 ,  C07C309/17

CPC classification number: C07D495/04 ,  C07C309/17

Abstract: Docusate salts of N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N′-(3-fluorophenyl)urea are suitable pharmaceutical ingredients for pharmaceutical compositions useful in the treatment of disease, for example, cancer.