公开(公告)号：US20150216563A1

公开(公告)日：2015-08-06

申请号：US14617842

申请日：2015-02-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Evgenia Mandrusov ,  Albert K. Chin ,  William Earl Webler, JR. ,  Yan Shen ,  Robert D. Ainsworth ,  Eugene Michal

IPC: A61B17/34 ,  A61M5/00 ,  A61B1/313 ,  A61K35/28 ,  A61B1/015

CPC classification number: A61B17/3472 ,  A61B1/015 ,  A61B1/313 ,  A61B2017/00969 ,  A61B2217/005 ,  A61K35/28 ,  A61K2035/124 ,  A61M5/00 ,  A61M2202/10 ,  A61M2210/02 ,  A61M2210/125

Abstract: Numerous embodiments of a system and method for treating cardiac tissue are described. In one embodiment, bone marrow cells are extracted from a patient. The cells are then processed to isolate mononuclear cells, which can then be delivered back near the cardiac tissue of the patient.

Abstract translation: 描述了用于治疗心脏组织的系统和方法的许多实施例。 在一个实施方案中，从患者中提取骨髓细胞。 然后处理细胞以分离单核细胞，其然后可以在患者的心脏组织附近被递送回来。

公开(公告)号：US09101697B2

公开(公告)日：2015-08-11

申请号：US14251489

申请日：2014-04-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed Faiyaz Ahmed Hossainy ,  Eugene Michal ,  Thierry Glauser ,  Connie Kwok ,  Stephen Dirk Pacetti

IPC: A61K31/44 ,  A61L31/10 ,  A61K31/727 ,  A61K31/728 ,  A61K31/785 ,  A61L31/16

CPC classification number: A61L31/10 ,  A61K31/727 ,  A61K31/728 ,  A61K31/785 ,  A61L31/16 ,  A61K2300/00 ,  C08L5/08 ,  C08L5/10

Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.

Abstract translation: 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。

公开(公告)号：US20140221418A1

公开(公告)日：2014-08-07

申请号：US14251489

申请日：2014-04-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed Faiyaz Ahmed Hossainy ,  Eugene Michal ,  Thierry Glauser ,  Connie Kwok ,  Stephen Dirk Pacetti

IPC: A61L31/10 ,  A61L31/16

CPC classification number: A61L31/10 ,  A61K31/727 ,  A61K31/728 ,  A61K31/785 ,  A61L31/16 ,  A61K2300/00 ,  C08L5/08 ,  C08L5/10

Abstract: Hyaluronic acid (HA) conjugates or crosslinked HAs compositions for coating an implantable device are provided. The implantable device can be used for treating a disorder such as atherosclerosis, thrombosis, restenosis, high cholesterol, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.

Abstract translation: 提供了用于涂覆可植入装置的透明质酸（HA）缀合物或交联的HA组合物。 可植入装置可用于治疗动脉粥样硬化，血栓形成，再狭窄，高胆固醇，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍，胆管 梗阻，输尿管阻塞，肿瘤阻塞及其组合。